| 274 | Chen HY, de Kouchkovsky I, Bok RA, Ohliger MA, Wang ZJ, Gebrezgiabhier D, Nickles T, Carvajal L, Gordon JW, Larson PEZ, Kurhanewicz J, Aggarwal R, Vigneron DB. Multivariate Framework of Metabolism in Advanced Prostate Cancer Using Whole Abdominal and Pelvic Hyperpolarized 13C MRI-A Correlative Study with Clinical Outcomes. Cancers (Basel). 2025; 17(13):2211. PMCID: PMC12248915 |
| 273 | Punwani S, Larson PEZ, Laustsen C, VanderMeulen J, Ardenkjær-Larsen JH, Autry AW, Bankson JA, Bernard J, Bok R, Bertelsen LB, Che J, Chen AP, Chowdhury R, Comment A, Cunningham CH, Dang D, Gallagher FA, Gaunt A, Gong Y, Gordon JW, Grimmer A, Grist J, Hansen ESS, Lerche MH, Hesketh RL, Hoevener JB, Hsieh CY, Keshari KR, Kozerke S, Lanz T, Mayer D, McLean M, Park JM, Slater J, Tyler D, Vanderheyden JL, von Morze C, Zaccagna F, Zaha V, Xu D, Vigneron D; HP 13C MRI Consensus Group. Consensus recommendations for hyperpolarized [1-13C]pyruvate MRI multi-center human studies. Magn Reson Med. 2025; 94(4):1386-1400. doi: 10.1002/mrm.30570. PMCID: PMC12236423 |
| 272 | Kim Y, Chen HY, Nickles T, Shkliar I, Dang D, Slater J, Wang C, Gordon JW, Tan CT, Suszczynski C, Maddali S, Gaunt A, Chen R, Villanueva-Meyer J, Xu D, Larson PEZ, Kurhanewicz J, Bok RA, Chang S, Vigneron DB. Translation of hyperpolarized [13C,15N2]urea MRI for novel human brain perfusion studies. Npj Imaging. 2025; 3(1):11. PMCID: PMC11925798 |
| 271 | Liu X, Cui D, Larson PEZ, Mayer D, Korzowski A, Nielsen JF, Schulte RF, Mu C, Carvajal L, Xu D, Gordon JW, Vigneron DB, Flavell RR, Wang ZJ. Open-source implementation of X-nuclear sequences using the Pulseq framework. Magn Reson Med. 2025; 94(2):651-664. PMCID: PMC12140903 |
| 270 | Autry AW, Kim Y, Dang D, Chen HY, Slater JB, Bok RA, Xu D, Lupo JM, Gordon JW, Larson PEZ, Vigneron DB, Li Y, Chang SM. Clinical Translation of Hyperpolarized 13C Metabolic Probes for Glioma Imaging. AJNR Am J Neuroradiol. 2025 Mar 5:ajnr.A8726. doi: 10.3174/ajnr.A8726. Epub ahead of print. PMID: 40044455 |
| 269 | Kim Y, Nickles TM, Lee PM, Bok RA, Gordon JW, Larson PEZ, Vigneron DB, von Morze C, Ohliger MA. A data-driven approach for improved quantification of in vivo metabolic conversion rates of hyperpolarized [1-13C]pyruvate. Magn Reson Med. 2025; 93(6):2346-2356. doi: 10.1002/mrm.30445. PMCID: PMC11971488 |
| 268 | Sahin S, Haller AB, Gordon J, Kim Y, Hu J, Nickles T, Dai Q, Leynes AP, Vigneron DB, Wang ZJ, Larson PEZ. Spatially constrained hyperpolarized 13C MRI pharmacokinetic rate constant map estimation using a digital brain phantom and a U-Net. J Magn Reson. 2025; 371:107832. doi: 10.1016/j.jmr.2025.107832. PMCID: PMC11807744 |
| 267 | Liu X, Lai YC, Cui D, Kung SC, Park M, Laszik Z, Larson PEZ, Wang ZJ. Initial Experience of Metabolic Imaging With Hyperpolarized [1-13C]]pyruvate MRI in Kidney Transplant Patients. ArXiv [Preprint]. 2024 Sep 10:arXiv:2409.06664v1. PMCID: PMC11419194 |
| 266 | de Kouchkovsky I, Nguyen H, Chen HY, Liu X, Qin H, Stoher BA, Delos Santos R, Ohliger MA,Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Gebrezgiabhier D, Cooperberg M, Vigneron DB, Kurhanewicz J, Aggarwal R. Dual hyperpolarized [1-13C]pyruvate and [13C]urea magnetic resonance imaging of prostate cancer. JMRO. 2024 December: (21)100165. doi.org/10.1016/j.jmro.2024.100165. Epub ahead of print |
| 265 | Mu C, Liu X, Riselli A, Slater J, Escobar E, Dang D, Drapeau S, Delos Santos R, Andosca S, Nguyen H, Larson PEZ, Bok R, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR. Protocol for producing hyperpolarized 13C-bicarbonate for clinical MRI of extracellular pH in aggressive tumors. STAR Protoc. 2024; 5(3):103091. PMCID: PMC11261128 |
| 264 | von Morze C, Blazey T, Shaw A, Spees WM, Shoghi KI, Ohliger MA. Detection of early-stage NASH using non-invasive hyperpolarized 13C metabolic imaging. Sci Rep. 2024; 14(1):14854. PMCID: PMC11211431 |
| 263 | Sahin S, Garnæs MF, Bennett A, Dwork N, Tang S, Liu X, Vaidya M, Wang ZJ, Larson PEZ. A pharmacokinetic model for hyperpolarized 13C-pyruvate MRI when using metabolite-specific bSSFP sequences. Magn Reson Med. 2024; 92(4):1698-1713. PMCID: PMC1126297 |
| 262 | Liu X, Manninen T, Capper AM, Jiang X, Ellison J, Kim Y, Gurler G, Xu D, Ferriero DM. Brain metabolism after therapeutic hypothermia for murine hypoxia-ischemia using hyperpolarized [1-13C] pyruvate magnetic resonance spectroscopy. NMR Biomed. 2024; 37(10):e5196. doi: 10.1002/nbm.5196. PMCID: PMC11839149 |
| 261 | Diaz E, Sriram R, Gordon JW, Sinha A, Liu X, Sahin SI, Crane JC, Olson MP, Chen HY, Bernard JML, Vigneron DB, Wang ZJ, Xu D, Larson PEZ. Data Format Standardization and DICOM Integration for Hyperpolarized 13C MRI. J Imaging Inform Med. 2024; 37(5):2627-2634. PMCID: PMC11522264 |
| 260 | Agarwal S, Gordon J, Bok RA, von Morze C, Vigneron DB, Kurhanewicz J, Ohliger MA. Distinguishing metabolic signals of liver tumors from surrounding liver cells using hyperpolarized 13C MRI and gadoxetate. Med. 2024; 91(5):2114-2125. PMID: 38270193 |
| 259 | Autry AW, Vaziri S, Gordon JW, Chen HY, Kim Y, Dang D, LaFontaine M, Noeske R, Bok R, Villanueva-Meyer JE, Clarke JL, Oberheim Bush NA, Chang SM, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Li Y. Advanced Hyperpolarized 13C Metabolic Imaging Protocol for Patients with Gliomas: A Comprehensive Multimodal MRI Approach. Cancers (Basel). 2024;16(2):354. PMCID: PMC10814348 |
| 258 | Gordon JW, Chen HY, Nickles T, Lee PM, Bok R, Ohliger MA, Okamoto K, Ko AH, Larson PEZ, Wang ZJ. Hyperpolarized 13C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma. J Magn Reson Imaging. 2024; 60(2):741-749. PMCID: PMC11144260 |
| 257 | Chaumeil MM, Bankson JA, Brindle KM, Epstein S, Gallagher FA, Grashei M, Guglielmetti C, Kaggie JD, Keshari KR, Knecht S, Laustsen C, Schmidt AB, Vigneron D, Yen YF, Schilling F. New Horizons in Hyperpolarized 13C MRI. Mol Imaging Biol. 2024; 26(2):222-232. PMCID: PMC10972948 |
| 256 | Larson PEZ, Tang S, Liu X, Sinha A, Dwork N, Sivalokanathan S, Liu J, Bok R, Ordovas KG, Slater J, Gordon JW, Abraham MR. Regional quantification of cardiac metabolism with hyperpolarized [1-13C]-pyruvate CMR evaluated in an oral glucose challenge. J Cardiovasc Magn Reson. 2023; 25(1):77. PMCID: PMC10720165 |
| 255 | Piraquive Agudelo J, Kim Y, Agarwal S, Sriram R, Bok R, Kurhanewicz J, Mattis AN, Maher JJ, von Morze C, Ohliger MA. Hyperpolarized [1-13C] pyruvate MRSI to detect metabolic changes in liver in a methionine and choline-deficient diet rat model of fatty liver disease. Magn Reson Med. 2024; 91(4):1625-1636. PMCID: PMC11032123 |
| 254 | Gammon ST, Cohen AS, Lehnert AL, Sullivan DC, Malyarenko D, Manning HC, Hormuth DA, Daldrup-Link HE, An H, Quirk JD, Shoghi K, Pagel MD, Kinahan PE, Miyaoka RS, Houghton AM, Lewis MT, Larson P, Sriram R, Blocker SJ, Pickup S, Badea A, Badea CT, Yankeelov TE, Chenevert TL. An Online Repository for Pre-Clinical Imaging Protocols (PIPs). Tomography. 2023; 9(2):750-758. PMCID: PMC10145184 |
| 253 | Moore SM, Quirk JD, Lassiter AW, Laforest R, Ayers GD, Badea CT, Fedorov AY, Kinahan PE, Holbrook M, Larson PEZ, Sriram R, Chenevert TL, Malyarenko D, Kurhanewicz J, Houghton AM, Ross BD, Pickup S, Gee JC, Zhou R, Gammon ST, Manning HC, Roudi R, Daldrup-Link HE, Lewis MT, Rubin DL, Yankeelov TE, Shoghi KI. Co-Clinical Imaging Metadata Information (CIMI) for Cancer Research to Promote Open Science, Standardization, and Reproducibility in Preclinical Imaging. Tomography. 2023; 11;9(3):995-1009. PMCID: PMC10204428 |
| 252 | Nickles TM, Kim Y, Lee PM, Chen HY, Ohliger M, Bok RA, Wang ZJ, Larson PEZ, Vigneron DB, Gordon JW. Hyperpolarized 13C Metabolic Imaging of the Human Abdomen with Spatiotemporal Denoising. Magn Reson Med. 2024; 91(5):2153-2161. PMCID: PMC10950515 |
| 251 | Yeste J, Azagra M, Ortega MA, Portela A, Matajsz G, Herrero-Gómez A, Kim Y, Sriram R, Kurhanewicz J, Vigneron DB, Marco-Rius I. Parallel detection of chemical reactions in a microfluidic platform using hyperpolarized nuclear magnetic resonance. Lab Chip. 2023; 23(23):4950-4958. PMCID: PMC10661666 |
| 250 | Liu X, Cui D, Xu D, Bok R, Wang ZJ, Vigneron DB, Larson PEZ, Gordon JW. Dynamic T2* relaxometry of hyperpolarized [1-13C]pyruvate MRI in the human brain and kidneys. Magn Reson Med. 2024; 91(3):1030-1042. PMCID: PMC10872504 |
| 249 | Hong D, Kim Y, Mushti C, Minami N, Wu J, Cherukuri MK, Swenson RE, Vigneron DB, Ronen SM. Monitoring response to a clinically relevant IDH inhibitor in glioma-Hyperpolarized 13C magnetic resonance spectroscopy approaches. Neurooncol Adv. 2023; 5(1):vdad143. doi: 10.1093/noajnl/vdad143. PMCID: PMC10681661 |
| 248 | Chen HY, Gordon JW, Dwork N, Chung BT, Riselli A, Sivalokanathan S, Bok RA, Slater JB, Vigneron DB, Abraham MR, Larson PEZ. Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2- 13C ]Pyruvate MR Spectroscopy. NMR Biomed. 2024; 37(3):e5074. PMCID: PMC10615004 |
| 247 | Mu C, Liu X, Kim Y, Riselli A, Korenchan DE, Bok RA, Delos Santos R, Sriram R, Qin H, Nguyen H, Gordon JW, Slater J, Larson PEZ, Vigneron DB, Kurhanewicz J, Wilson DM, Flavell RR. Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer. ACS Sens. 2023; 8(11):4042-4054. PMCID: PMC10683509 |
| 246 | Larson PE, Bernard JM, Bankson JA, Bøgh N, Bok RA, Chen AP, Cunningham CH, Gordon J, Hövener JB, Laustsen C, Mayer D, McLean MA, Schilling F, Slater J, Vanderheyden JL, von Morze C, Vigneron DB, Xu D, Group THCMC. Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies. Magn Reson Med. 2024; 91(6):2204-2228. PMCID: PMC10997462 |
| 245 | Hu J, Vaziri S, Bogh N, Kim Y, Autry AW, Bok RA, Li Y, Laustsen C, Xu D, Larson PEZ, Chang S, Vigneron DB, Gordon JW. Investigating Cerebral Perfusion with High Resolution Hyperpolarized [1-13C]Pyruvate MRI. Magn Reson Med. 2023; 90(6):2233-2241. PMCID: PMC10543485 |
| 244 | Batsios G, Taglang C, Gillespie AM, Viswanath P. Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-13C]-gluconolactone. Neurooncol Adv. 2023; 5(1):vdad092. PMCID: PMC10433788 |
| 243 | Autry AW, Vaziri S, LaFontaine M, Gordon JW, Chen HY, Kim Y, Villanueva-Meyer JE, Molinaro A, Clarke JL, Oberheim Bush NA, Xu D, Lupo JM, Larson PEZ, Vigneron DB, Chang SM, Li Y. Multi-parametric hyperpolarized 13C/1H imaging reveals Warburg-related metabolic dysfunction and associated regional heterogeneity in high-grade human gliomas. Neuroimage Clin. 2023; 39:103501. doi: 10.1016/j.nicl.2023.103501. PMCID: PMC10470324 |
| 242 | Chaumeil M, Guglielmetti C, Qiao K, Tiret B, Ozen M, Krukowski K, Nolan A, Paladini MS, Lopez C, Rosi S. Hyperpolarized 13C metabolic imaging detects long-lasting metabolic alterations following mild repetitive traumatic brain injury. Res Sq. 2023 Aug 14:rs.3.rs-3166656. PMCID: PMC10462249 |
| 241 | Chung BT, Kim Y, Gordon JW, Chen HY, Autry AW, Lee PM, Hu JY, Tan CT, Suszczynski C, Chang SM, Villaneuva-Meyer JE, Bok RA, Larson PEZ, Xu D, Li Y, Vigneron DB. Hyperpolarized [2-13C]Pyruvate MR Molecular Imaging with Whole Brain Coverage. Neuroimage. 2023; 280:120350. doi: 10.1016/j.neuroimage.2023.120350. PMCID: PMC10530049 |
| 240 | Christensen NV, Vaeggemose M, Bøgh N, Hansen ESS, Olesen JL, Kim Y, Vigneron DB, Gordon JW, Jespersen SN, Laustsen C. A user independent denoising method for x-nuclei MRI and MRS. Magn Reson Med. 2023 Aug 1. doi: 10.1002/mrm.29817. Epub ahead of print. PMID: 37526128 |
| 239 | Liu X, Tang S, Cui D, Bok RA, Chen HY, Gordon JW, Wang ZJ, Larson PEZ. A metabolite specific 3D stack-of-spirals bSSFP sequence for improved bicarbonate imaging in hyperpolarized [1-13C]Pyruvate MRI. J Magn Reson. 2023; 353:107518. PMCID: PMC10498937 |
| 238 | Sahin SI, Ji X, Agarwal S, Sinha A, Mali I, Gordon JW, Mattingly M, Subramaniam S, Kurhanewicz J, Larson PEZ, Sriram R. Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI. Tomography. 2023; 9(2):736-749. PMCID: PMC10143874 |
| 237 | Guarin DO, Joshi SM, Samoilenko A, Kabir MSH, Hardy EE, Takahashi AM, Ardenkjaer-Larsen JH, Chekmenev EY, Yen YF. Development of Dissolution Dynamic Nuclear Polarization of [15N3]Metronidazole: a Clinical Approved Antibiotic. Angew Chem Int Ed Engl. 2023; 62(31):e202219181. PMCID: PMC10524734 |
| 236 | Guglielmetti C, Cordano C, Najac C, Green AJ, Chaumeil MM. Imaging immunomodulatory treatment responses in a multiple sclerosis mouse model using hyperpolarized 13C metabolic MRI. Commun Med (Lond). 2023; 3(1):71. PMCID: PMC10202949 |
| 235 | Minami N, Hong D, Taglang C, Batsios G, Gillespie AM, Viswanath P, Stevers N, Barger CJ, Costello JF, Ronen SM. Hyperpolarized δ-[1-13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma. Sci Rep. 2023; 13(1):5190. PMCID: PMC10063634 |
| 234 | Peehl DM, Badea CT, Chenevert TL, Daldrup-Link HE, Ding L, Dobrolecki LE, Houghton AM, Kinahan PE, Kurhanewicz J, Lewis MT, Li S, Luker GD, Ma CX, Manning HC, Mowery YM, O’Dwyer PJ, Pautler RG, Rosen MA, Roudi R, Ross BD, Shoghi KI, Sriram R, Talpaz M, Wahl RL, Zhou R. Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials. Tomography. 2023; 9(2):657-680. PMCID: PMC10037611.12 |
| 233 | 2023 Publications (233 and above) Xu Z, Michel KA, Walker CM, Harlan CJ, Martinez GV, Gordon JW, Chen HY, Vigneron DB, Bankson JA. Model-constrained reconstruction accelerated with Fourier-based undersampling for hyperpolarized [1-13C]pyruvate imaging. Magn Reson Med. 2023; 89(4):1481-1495. PMCID: PMC9892212 |
| 232 | Agudelo JP, Upadhyay D, Zhang D, Zhao H, Nolley R, Sun J, Agarwal S, Bok RA, Vigneron DB, Brooks JD, Kurhanewicz J, Peehl DM, Sriram R. Multiparametric Magnetic Resonance Imaging and Metabolic Characterization of Patient-Derived Xenograft Models of Clear Cell Renal Cell Carcinoma. Metabolites. 2022; 12(11):1117. PMCID: PMC9692472 |
| 231 | Vaidya MV, Zhang B, Hong D, Brown R, Batsios G, Viswanath P, Paska J, Wulf G, Grant AK, Ronen SM, Larson PEZ. A 13C/31P surface coil to visualize metabolism and energetics in the rodent brain at 3 Tesla. J Magn Reson. 2022; 343:107286. PMCID: PMC9721620 |
| 230 | Vaziri S, Autry AW, Lafontaine M, Kim Y, Gordon JW, Chen HY, Hu JY, Lupo JM, Chang SM, Clarke JL, Villanueva-Meyer JE, Bush NAO, Xu D, Larson PEZ, Vigneron DB, Li Y. Assessment of higher-order singular value decomposition denoising methods on dynamic hyperpolarized [1-13C]pyruvate MRI data from patients with glioma. Neuroimage Clin. 2022; 36: 103155. PMCID: PMC9421383 |
| 229 | Chen HY, Bok RA, Cooperberg MR, Nguyen HG, Shinohara K, Westphalen AC, Wang ZJ, Ohliger MA, Gebrezgiabhier D, Carvajal L, Gordon JW, Larson PEZ, Aggarwal R, Kurhanewicz J, Vigneron DB. Improving Multiparametric MR-Transrectal ultrasound Guided Fusion Prostate biopsies with Hyperpolarized 13C Pyruvate Metabolic imaging: A technical development study. Magn Reson Med. 2022; 88(6):2609-2620. PPMC9794017 |
| 228 | Miloushev VZ, Boltyanskiy R, Granlund KL, Keshari KR. Improved total sensitivity estimation for multiple receive coils in MRI using ratios of first-order statistics. MAGMA. 2022; 35(6):895-901. PMCID: PMC9613615 |
| 227 | Hu JY, Kim Y, Autry AW, Frost MM, Bok RA, Villanueva-Meyer JE, Xu D, Li Y, Larson PEZ, Vigneron DB, Gordon JW. Kinetic analysis of multi-resolution hyperpolarized 13C human brain MRI to study cerebral metabolism. Magn Reson Med. 2022; 88(5):2190-2197. PMCID: PMC9420752 |
| 226 | Liu X, Tang S, Mu C, Qin H, Cui D, Lai YC, Riselli AM, Delos Santos R, Carvajal L, Gebrezgiabhier D, Bok RA, Chen HY, Flavell RR, Gordon JW, Vigneron DB, Kurhanewicz J, Larson PEZ. Development of specialized magnetic resonance acquisition techniques for human hyperpolarized [13C,15N2]urea + [1-13C]pyruvate simultaneous perfusion and metabolic imaging. Magn Reson Med. 2022; 88(3):1039-1054. PMCID: PMC9810116 |
| 225 | Minami N, Hong D, Stevers N, Barger CJ, Radoul M, Hong C, Chen L, Kim Y, Batsios G, Gillespie AM, Pieper RO, Costello JF, Viswanath P, Ronen SM. Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma. Neuro Oncol. 2022; 24(11):1898-1910. PMCID: PMC9629440 |
| 224 | Ragavan M, McLeod MA, Rushin A, Merritt ME. Detecting de novo Hepatic Ketogenesis Using Hyperpolarized [2-13C] Pyruvate. Front Physiol. 2022; 7(13):832403. PMCID: PMC8859440 |
| 223 | Ye Z, Song B, Lee PM, Ohliger MA, Laustsen C. Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities. Liver Int. 2022; 42(5):973-983. PMCID: PMC9313895 |
| 222 | Saito Y, Yatabe H, Tamura I, Kondo Y, Ishida R, Seki T, Hiraga K, Eguchi A, Takakusagi Y, Saito K, Oshima N, Ishikita H, Yamamoto K, Krishna MC, Sando S. Structure-guided design enables development of a hyperpolarized molecular probe for the detection of aminopeptidase N activity in vivo. Sci Adv. 2022; 8(13):eabj2667. PMCID: PMC8967239 |
| 221 | Lee PM, Chen HY, Gordon JW, Wang ZJ, Bok R, Hashoian R, Kim Y, Liu X, Nickles T, Cheung K, Alas FL, Daniel H, Larson PEZ, von Morze C, Vigneron DB, Ohliger MA. Whole-Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1-13C]pyruvate MRI. J Magn Reson Imaging. 2022; 56(6):1792-1806. PMCID: PMC9562149 |
| 220 | Bøgh N, Gordon JW, Hansen ESS, Bok RA, Blicher JU, Hu JY, Larson PEZ, Vigneron DB, Laustsen C. Initial Experience on Hyperpolarized [1-13C]Pyruvate MRI Multicenter Reproducibility-Are Multicenter Trials Feasible? Tomography. 2022; 8(2):585-595. PMCID: PMC8938827 |
| 219 | Schmidt AB, Bowers CR, Buckenmaier K, Chekmenev EY, de Maissin H, Eills J, Ellermann F, Glöggler S, Gordon JW, Knecht S, Koptyug IV, Kuhn J, Pravdivtsev AN, Reineri F, Theis T, Them K, Hövener JB. Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques. Anal Chem. 2022; 94(1):479-502. PMCID: PMC8784962 |
| 218 | Hong D, Batsios G, Viswanath P, Gillespie AM, Vaidya M, Larson PEZ, Ronen SM. Acquisition and quantification pipeline for in vivo hyperpolarized 13C MR spectroscopy. Magn Reson Med. 2022; 87(4):1673-1687. PMCID: PMC8830804 |
| 217 | de Kouchkovsky I, Chen HY, Ohliger MA, Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Cooperberg MR, Kurhanewicz J, Vigneron DB, Aggarwal R. Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Immune Checkpoint Inhibitor Therapy in Prostate Cancer. Eur Urol. 2022; 81(2):219-221. PMCID: PMC9275093 |
| 216 | Qin H, Tang S, Riselli AM, Bok RA, Delos Santos R, van Criekinge M, Gordon JW, Aggarwal R, Chen R, Goddard G, Zhang CT, Chen A, Reed G, Ruscitto DM, Slater J, Sriram R, Larson PEZ, Vigneron DB, Kurhanewicz J. Clinical translation of hyperpolarized 13C pyruvate and urea MRI for simultaneous metabolic and perfusion imaging. Magn Reson Med. 2022; 87(1):138-149. PMCID: PMC8616838 |
| 215 | Ma J, Malloy CR, Pena S, Harrison CE, Ratnakar J, Zaha VG, Park JM. Dual-phase imaging of cardiac metabolism using hyperpolarized pyruvate. Magn Reson Med. 2022; 87(1):302-211. PMCID: PMC8616832 |
| 214 | Lee SJ, Park I, Talbott JF, Gordon J. Investigating the Feasibility of In Vivo Perfusion Imaging Methods for Spinal Cord Using Hyperpolarized [13C]t-Butanol and [13C,15N2]Urea. Eur Urol. 2022; 81(2): 219-221. PMCID: PMC9275093 |
| 213 | 2022 Publications (213 and above)
Ma J, Pinho MC, Harrison CE, Chen J, Sun C, Hackett EP, Liticker J, Ratnakar J, Reed GD, Chen AP, Sherry AD, Malloy CR, Wright SM, Madden CJ, Park JM. Dynamic 13C MR spectroscopy as an alternative to imaging for assessing cerebral metabolism using hyperpolarized pyruvate in humans. Mol Imaging Biol. 2022; 24(3):371-376. PMID: 34779970 |
| 212 | Singh J, Suh EH, Sharma G, Chen J, Hackett EP, Wen X, Sherry AD, Khemtong C, Malloy CR, Park JM, Kovacs Z. 13C-Labeled Diethyl Ketoglutarate Derivatives as Hyperpolarized Probes of 2-Ketoglutarate Dehydrogenase Activity. Anal Sens. 2021; 1(4): 156-160. PMCID: PMC9165698 |
| 211 | Lee CY, Soliman H, Bragagnolo ND, Sahgal A, Geraghty BJ, Chen AP, Endre R, Perks WJ, Detsky JS, Leung E, Chan M, Heyn C, Cunningham CH. Predicting response to radiotherapy of intracranial metastases with hyperpolarized 13C MRI. J Neurooncol. 2021; 152(3):551-557. PMCID: PMC8084843 |
| 210 | von Morze C, Blazey T, Baeza R, Garipov R, Whitehead T, Reed GD, Garbow JR, Shoghi KI. Multi-band echo-planar spectroscopic imaging of hyperpolarized 13C probes in a compact preclinical PET/MR scanner. Magn Reson Med. 2021; 87(5):2120-2129. PMID: 34971459 |
| 209 | Sharma G, Wen X, Maptue NR, Hever T, Malloy CR, Sherry AD, Khemtong C. Co-Polarized [1-13C]Pyruvate and [1,3-13C2]Acetoacetate Provide a Simultaneous View of Cytosolic and Mitochondrial Redox in a Single Experiment. ACS Sens. 2021; 6(11): 3967-3977. PMCID: PMC8908480 |
| 208 | AbuSalim JE, Yamamoto K, Miura N, Blackman B, Brender JR, Mushti C, Seki T, Camphausen KA, Swenson RE, Krishna MC, Kesarwala AH. Simple Esterification of [1-13C]-Alpha-Ketoglutarate Enhances Membrane Permeability and Allows for Noninvasive Tracing of Glutamate and Glutamine Production. ACS Chem Biol. 2021; 16(11):2144-2150. PMCID: PMC9107957 |
| 207 | Park JM, Josan S, Hurd RE, Graham J, Havel PJ, Bendahan D, Mayer D, Chung Y, Spielman DM, Jue T. Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle. Pflugers Arch. 2021; 473(11):1761-1773. PMCID: PMC9219576 |
| 206 | Chen J, Patel TR, Pinho MC, Choi C, Harrison CE, Baxter JD, Derner K, Pena S, Liticker J, Raza J, Hall RG, Reed GD, Cai C, Hatanpaa KJ, Bankson JA, Bachoo RM, Malloy CR, Mickey BE, Park JM. Preoperative imaging of glioblastoma patients using hyperpolarized 13C pyruvate: Potential role in clinical decision making. Neurooncol Adv. 2021; 3(1):vdab092. PMCID: PMC8331053 |
| 205 | Ragavan M, McLeod MA, Giacalone AG, Merritt ME. Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State. Metabolites. 2021; 11(7):441. doi: 10.3390/metabo11070441. PMCID: PMC8307483 |
| 204 | Blazey, T, Reed, GD, Garbow, JR, von Morze C. Metabolite-Specific Echo-Planar Imaging of Hyperpolarized [1-13C]Pyruvate at 4.7 T. Tomography. 2021; 7(3):466-476. PMCID: PMC8482109 |
| 203 | Li Y, Vigneron DB, Xu D. Current human brain applications and challenges of dynamic hyperpolarized carbon-13 labeled pyruvate MR metabolic imaging. Eur J Nucl Med Mol Imaging. 2021; 48(13):4225-4235. PMCID: PMC8566394 |
| 202 | Miura N, Mushti C, Sail D, AbuSalim JE, Yamamoto K, Brender JR, Seki T, AbuSalim DI, Matsumoto S, Camphausen KA, Krishna MC, Swenson RE, Kesarwala AH. Synthesis of [1-13C-5-12C]-alpha-ketoglutarate enables noninvasive detection of 2-hydroxyglutarate. NMR Biomed. 2021; 34(11):e4588. PMCID: PMC8492538 |
| 201 | Harlan CJ, Xu Z, Walker CM, Michel KA, Reed GD, Bankson JA. The Effect of Transmit B1 Inhomogeneity on Hyperpolarized [1-13C]-Pyruvate Metabolic MR Imaging Biomarkers. Med Phys. 2021; 48(9):4900-4908. PMCID: PMC8486175 |
| 200 | Larson PEZ, Gordon JW. Hyperpolarized Metabolic MRI-Acquisition, Reconstruction, and Analysis Methods. Metabolites. 2021; 11(6):386.PMCID: PMC8231874 |
| 199 | Park JM, Harrison CE, Ma J, Chen J, Ratnakar J, Zun Z, Liticker J, Reed GD, Chhabra A, Haller RG, Jue T, Malloy CR. Hyperpolarized 13C MR Spectroscopy Depicts in Vivo Effect of Exercise on Pyruvate Metabolism in Human Skeletal Muscle. Radiology. 2021; 300(3):626-632. PMCID: PMC8409104 |
| 198 | Yamamoto K, Opina A, Sail D, Blackman B, Saito K, Brender JR, Malinowski RM, Seki T, Oshima N, Crooks DR, Kishimoto S, Saida Y, Otowa Y, Choyke PL, Ardenkjær-Larsen JH, Mitchell JB, Linehan WM, Swenson RE, Krishna MC. Real-Time insight into in vivo redox status utilizing hyperpolarized [1-13C] N-acetyl cysteine. Sci Rep. 2021; 11(1):12155. PMCID: PMC8190077 |
| 197 | Saida Y, Brender JR, Yamamoto K, Mitchell JB, Krishna MC, Kishimoto S. Multimodal molecular imaging detects early responses to immune checkpoint blockade. Cancer Res. 2021; 81(13): 3693-3705. PMCID: PMC8277685 |
| 196 | Lee PM, Chen HY, Gordon JW, Zhu Z, Larson PEZ, Dwork N, Van Criekinge M, Carvajal L, Ohliger MA, Wang ZJ, Xu D, Kurhanewicz J, Bok RA, Aggarwal R, Munster PN, Vigneron DB. Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13C MR EPSI studies of liver tumors. Magn Reson Med. 2021; 86(5):2402-2411. PMCID: PMC8565779 |
| 195 | Kim Y, Chen HY, Autry AW, Villanueva-Meyer J, Chang SM, Li Y, Larson PEZ, Brender JR, Krishna MC, Xu D, Vigneron DB, Gordon JW. Denoising of hyperpolarized 13C MR images of the human brain using patch-based higher-order singular value decomposition. Magn Reson Med. 2021; 86(5):2497-2511. PMCID: PMC8530853 |
| 194 | Kawai T, Brender JR, Lee JA, Kramp T, Kishimoto S, Krishna MC, Tofilon P, Camphausen KA. Detection of metabolic change in glioblastoma cells after radiotherapy using hyperpolarized 13C-MRI. NMR Biomed. 2021; 34(7):e4514. PMCID: PMC8243917 |
| 193 | Batsios G, Taglang C, Cao P, Gillespie AM, Najac C, Subramani E, Wilson DM, Flavell RR, Larson PEZ, Ronen SM, Viswanath P. Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone. Front Oncol. 2021; 11:589570. PMCID: PMC8082394 |
| 192 | Lv X, Walton JH, Druga E, Wang F, Aguilar A, McKnelly T, Nazaryan R, Liu FL, Wu L, Shenderova O, Vigneron DB, Meriles CA, Reimer JA, Pines A, Ajoy A. Background-free dual-mode optical and 13C magnetic resonance imaging in diamond particles. Proc Natl Acad Sci USA. 2021; 118(21):e2023579118. PMCID: PMC8166172 |
| 191 | Bøgh N, Olin RB, Hansen ES, Gordon JW, Bech SK, Bertelsen LB, Sánchez-Heredia JD, Blicher JU, Østergaard L, Ardenkjær-Larsen JH, Bok RA, Vigneron DB, Laustsen C. Metabolic MRI with hyperpolarized [1-13C]pyruvate separates benign oligemia from infarcting penumbra in porcine stroke. J Cereb Blood Flow Metab. 2021; 41(11):2916-2927. PMCID: PMC8756460 |
| 190 | Viswanath P, Batsios G, Ayyappan V, Taglang C, Gillespie AM, Larson PEZ, Luchman HA, Costello JF, Pieper RO, Ronen SM. Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas. Neuro Oncol. 2021; 23(9):1509-1522. PMCID: PMC8408874 |
| 189 | Ma J, Chen J, Reed GD, Hackett EP, Harrison CE, Ratnakar J, Schulte RF, Zaha VG, Malloy CR, Park JM. Cardiac T2* measurement of hyperpolarized 13C metabolites using metabolite-selective multi-echo spiral imaging. Magn Reson Med. 2021; 86(3):1494-1504. PMCID: PMC8212421 |
| 188 | Tang S, Meng MV, Slater JB, Gordon JW, Vigneron DB, Stohr BA, Larson PEZ, Wang ZJ. Metabolic imaging with hyperpolarized 13C pyruvate magnetic resonance imaging in patients with renal tumors-Initial experience. Cancer. 2021; 127(15):2693-2704. PMCID: PMC8565774 |
| 187 | Dwork N, Gordon JW, Tang S, O'Connor D, Hansen ESS, Laustsen C, Larson PEZ. Di-chromatic interpolation of magnetic resonance metabolic images. MAGMA. 2021; 34(1):57-72. PMCID: PMC7983744 |
| 186 | Sun J, Bok RA, DeLos Santos J, Upadhyay D, DeLos Santos R, Agarwal S, Van Criekinge M, Vigneron DB, Aggarwal R, Peehl DM, Kurhanewicz J, Sriram R. Resistance to Androgen Deprivation Leads to Altered Metabolism in Human and Murine Prostate Cancer Cell and Tumor Models. Metabolites. 2021; 11(3):139. PMCID: PMC7996870 |
| 185 | Reed GD, Ma J, Park JM, Schulte RF, Harrison CE, Chen AP, Pena S, Baxter J, Derner K, Tai M, Raza J, Liticker J, Hall RG 2nd, Dean Sherry A, Zaha VG, Malloy CR. Characterization and compensation of f0 inhomogeneity artifact in spiral hyperpolarized 13C imaging of the human heart. Magn Reson Med. 2021; 86(1):157-166. PMCID: PMC8049085 |
| 184 | Ahamed F, Van Criekinge M, Wang ZJ, Kurhanewicz J, Larson P, Sriram R. Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models. NMR Biomed. 2021; 34(3): e4467. PMCID: PMC8423093 |
| 183 | Mu C, Korenchan DE, Wang S, Wilson DM, Flavell RR. Tumor Microenvironment Biosensors for Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopy. Mol Imaging Biol. 2021; 23(3):323-334. PMCID: PMC8105261 |
| 182 | Viswanath P, Batsios G, Mukherjee J, Gillespie AM, Larson PEZ, Luchman HA, Phillips JJ, Costello JF, Pieper RO, Ronen SM. Non-invasive assessment of telomere maintenance mechanisms in brain tumors. Nat Commun. 2021; 12(1): 92. PMCID: PMC7782549 |
| 181 | Datta K, Spielman D. MRI of [2-13C]Lactate without J-coupling artifacts. Magn Reson Med. 2021; 85(3): 1522-1539. PMCID: PMC7718337 |
| 180 | Ohliger MA, Gordon JW, Carvajal L, Larson PEZ, Ou JJ, Agarwal S, Zhu Z, Vigneron DB, von Morze C. 55Mn-based fiducial markers for rapid and automated RF coil localization for hyperpolarized 13C MRI. Magn Reson Med. 2021; 85(1):518-530. PMCID: PMC8354199 |
| 179 | Brender JR, Kishimoto S, Eaton GR, Eaton SS, Saida Y, Mitchell J, Krishna MC. Trehalose as an alternative to glycerol as a glassing agent for in vivo DNP MRI. Magn Reson Med. 2021; 85(1):42-48. PMCID: PMC9116131 |
| 178 | Crane JC, Gordon JW, Chen HY, Autry AW, Li Y, Olson MP, Kurhanewicz J, Vigneron DB, Larson PEZ, Xu D. Hyperpolarized 13C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco. NMR Biomed. 2021; 34(5): e4280. PMCID: PMC7501204 |
| 177 | Gordon JW, Chen HY, Dwork N, Tang S, Larson PEZ. Fast Imaging for Hyperpolarized MR Metabolic Imaging. J Magn Reson Imaging. 2021; 53(3):686-702. PMCID: PMC7415658. |
| 176 | 2021 Publications (176 and above)
Autry AW, Park I, Kline C, Chen HY, Gordon JW, Raber S, Hoffman C, Kim Y, Okamoto K, Vigneron DB, Lupo JM, Prados M, Li Y, Xu D, Mueller S. Pilot Study of Hyperpolarized 13C Metabolic Imaging in Pediatric Patients with Diffuse Intrinsic Pontine Glioma and Other CNS Cancers. Am J Neuroradiol. 2021; 42(1):178-184. PMCID: PMC7814790 |
| 175 | Rai G, Urban DJ, Mott BT, Hu X, Yang SM, Benavides GA, Johnson MS, Squadrito GL, Brimacombe KR, Lee TD, Cheff DM, Zhu H, Henderson MJ, Pohida K, Sulikowski GA, Dranow DM, Kabir M, Shah P, Padilha E, Tao D, Fang Y, Christov PP, Kim K, Jana S, Muttil P, Anderson T, Kunda NK, Hathaway HJ, Kusewitt DF, Oshima N, Cherukuri M, Davies DR, Norenberg JP, Sklar LA, Moore WJ, Dang CV, Stott GM, Neckers L, Flint AJ, Darley-Usmar VM, Simeonov A, Waterson AG, Jadhav A, Hall MD, Maloney DJ. Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. J Med Chem. 2020; 63(19): 10984-11011. PMCID: PMC7830743 |
| 174 | Subramani E, Radoul M, Najac C, Batsios G, Molloy AR, Hong D, Gillespie AM, Santos RD, Viswanath P, Costello JF, Pieper RO, Ronen SM. Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment. Cancer Res. 2020; 80(22): 5098-5108. PMCID: PMC7669718 |
| 173 | Park JM, Reed GD, Liticker J, Putnam WC, Chandra A, Yaros K, Afzal A, MacNamara JP, Raza J, Hall RG, Baxter J, Derner K, Pena S, Kallem RR, Subramanyan I, Edpuganti V, Harrison C, Muthukumar A, Lewis C, Reddy S, Unni N, Klemow D, Syed S, Li HC, Cole SM, Froehlich T, Ayers CR, de Lemos JA, Malloy CR, Haley B, Zaha VG. Effect of Doxorubicin on Myocardial Bicarbonate Production from Pyruvate Dehydrogenase in Women with Breast Cancer. Circ Res. 2020; 4;127(14):1568-1570. PMCID: PMC7874930 |
| 172 | Mikrogeorgiou A, Chen Y, Lee BS, Bok R, Sheldon AR, Barkovich JA, Xu D, Ferriero DM. A Metabolomics Study of Hypoxia Ischemia during Mouse Brain Development Using Hyperpolarized 13C. Dev Neurosci. 2020; 42(1): 49-58. PMCID: PMC7497410 |
| 171 | Walker CM, Gordon JW, Xu Z, Michel KA, Li L, Larson PEZ, Vigneron DB, Bankson JA. Slice profile effects on quantitative analysis of hyperpolarized pyruvate. NMR Biomed. 2020; 33(10): e4373. PMCID: PMC7484340 |
| 170 | Molloy AR, Najac C, Viswanath P, Lakhani A, Subramani E, Batsios G, Radoul M, Gillespie AM, Pieper RO, Ronen SM. MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma. Theranostics. 2020; 10(19): 8757-8770. PMCID: PMC7392019 |
| 169 | Gordon JW, Autry AW, Tang S, Graham JY, Bok RA, Zhu X, Villanueva-Meyer JE, Li Y, Ohliger MA, Abraham MR, Xu D, Vigneron DB. Larson PEZ. A variable resolution approach for improved acquisition of hyperpolarized 13C metabolic MRI. Magn Reson Med. 2020; 84(6): 2943-2952. PMCID: PMC7719570 |
| 168 | Autry AW, Gordon JW, Chen HY, LaFontaine M, Bok R, Van Criekinge M, Slater JB, Carvajal L, Villanueva-Meyer JE, Chang SM, Clarke JL, Lupo JM, Xu D, Larson PEZ, Vigneron DB, Li Y. Characterization of serial hyperpolarized 13C metabolic imaging in patients with glioma. Neuroimage Clin. 2020; 27: 102323. PMCID: PMC7334458 |
| 167 | Chen HY, Autry AW, Brender JR, Kishimoto S, Krishna MC, Vareth M, Bok RA, Reed GD, Carvajal L, Gordon JW, van Criekinge M, Korenchan DE, Chen AP, Xu D, Li Y, Chang SM, Kurhanewicz J, Larson PEZ, Vigneron DB. Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13C MRSI. Magn Reson Med. 2020; 84(6): 3351-3365. PMCID: PMC7718428 |
| 166 | Le Page LM, Guglielmetti C, Taglang C, Chaumeil MM. Imaging Brain Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy. Trends Neurosci. 2020; 43(5): 343-354. PMCID: PMC7255622. |
| 165 | Batsios G, Najac C, Cao P, Viswanath P, Subramani E, Saito Y, Gillespie AM, Yoshihara HAI, Larson P, Sando S, Ronen SM. In vivo detection of y-glutamyl-transferase up-regulation in glioma using hyperpolarizedy-glutamyl-[1-13C]glycine. Sci Rep. 2020; 10(1): 6244. PMCID: PMC7148357 |
| 164 | Qin H, Zhang V, Bok RA, Santos RD, Cunha JA, Hsu IC, Santos JD, Lee JE, Sukumar S, Larson PEZ, Vigneron DB, Wilson DM, Sriram R, Kurhanewicz J. Simultaneous metabolic and perfusion imaging using hyperpolarized 13C MRI can evaluate early and dose-dependent responses to radiotherapy in a prostate cancer mouse model. Int J Radiat Oncol Biol Phys. 2020; 107(5): 887-896. PMCID: PMC7381368 |
| 163 | Sriram R, Van Criekinge M, DeLos Santos J, Ahamed F, Qin H, Nolley R, Santos RD, Tabatabai ZL, Bok RA, Keshari KR, Vigneron DB, Peehl DM, Kurhanewicz J. Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures. Cancers (Basel). 2020; 12(3). pii: E537. PMCID: PMC7139946 |
| 162 | Tang S, Bok R, Qin H, Reed G, VanCriekinge M, Delos Santos R, Overall W, Santos J, Gordon J, Wang ZJ, Vigneron DB, Larson PEZ. A metabolite-specific 3D stack-of-spiral bSSFP sequence for improved lactate imaging in hyperpolarized [1-13C]pyruvate studies on a 3T clinical scanner. Magn Reson Med. 2020; 84(3):1113-1125. PMCID: PMC7927572. |
| 161 | Milshteyn E, Reed GD, Gordon JW, von Morze C, Cao P, Tang S, Leynes AP, Larson PEZ, Vigneron DB. Simultaneous T1 and T2 mapping of hyperpolarized 13C compounds using the bSSFP sequence. J Magn Reson. 2020; 312: 106691. PMCID: PMC7227792 |
| 160 | Mammoli D, Gordon J, Autry A, Larson PEZ, Li Y, Chen HY, Chung B, Shin P, Van Criekinge M, Carvajal L, Slater JB, Bok R, Crane J, Xu D, Chang S, Vigneron DB. Kinetic Modeling of Hyperpolarized Carbon-13 Pyruvate Metabolism in the Human Brain. IEEE Trans Med Imaging. 2020; 39(2): 320-327. PMCID: PMC6939147 |
| 159 | Chen HY, Aggarwal R, Bok RA, Ohliger MA, Zhu Z, Lee P, Gordon JW, van Criekinge M, Carvajal L, Slater JB, Larson PEZ, Small EJ, Kurhanewicz J, Vigneron DB. Hyperpolarized 13C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study. Prostate Cancer Prostatic Dis. 2020; 23(2): 269-276. PMCID: PMC7196510 |
| 158 | 2020 Publications (158 and above)
Lee CY, Soliman H, Geraghty BJ, Chen AP, Connelly KA, Endre R, Perks WJ, Heyn C, Black SE, Cunningham CH. Lactate topography of the human brain using hyperpolarized 13C-MRI. Neuroimage. 2020; 204: 116202. PMID: 31557546 |
| 157 | Le Page LM, Guglielmetti C, Najac CF, Tiret B, Chaumeil MM. Hyperpolarized 13C magnetic resonance spectroscopy detects toxin-induced neuroinflammation in mice. NMR Biomed. 2019; 32(11):e4164. PMCID: PMC6817388 |
| 156 | Brender JR, Kishimoto S, Merkle H, Reed G, Hurd RE, Chen AP, Ardenkjaer-Larsen JH, Munasinghe J, Saito K, Seki T, Oshima N, Yamamoto K, Choyke PL, Mitchell J, Krishna MC. Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization. Sci Rep. 2019; 9(1):3410. PMCID: PMC6399318 |
| 155 | Bancroft Brown J, Sriram R, VanCriekinge M, Delos Santos R, Sun J, Tabatabai ZL, Shinohara K, Nguyen H, Peehl DM, Kurhanewicz J. NMR quantification of lactate production and efflux and glutamate fractional enrichment in living human prostate biopsies cultured with [1,6-13C2]glucose. Magn Reson Med. 2019; 82(2): 566-576. PMCID: PMC7150535 |
| 154 | Wang S, Korenchan DE, Perez PM, Taglang C, Hayes TR, Sriram R, Bok R, Hong AS, Wu Y, Li H, Wang Z, Kurhanewicz J, Wilson DM, Flavell RR. Amino Acid-Derived Sensors for Specific Zn2+ Detection Using Hyperpolarized 13C Magnetic Resonance Spectroscopy. Chemistry. 2019; 25(51): 11842-11846. PMCID: PMC6742520 |
| 153 | Korenchan DE, Bok R, Sriram R, Liu K, Santos RD, Qin H, Lobach I, Korn N, Wilson DM, Kurhanewicz J, Flavell RR. Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer. Oncotarget. 2019; 10(58): 6096-6110. PMCID: PMC6817439 |
| 152 | Chung BT, Chen HY, Gordon J, Mammoli D, Sriram R, Autry AW, Le Page LM, Chaumeil M, Shin P, Slater J, Tan CT, Suszczynski C, Chang S, Li Y, Bok RA, Ronen SM, Larson PEZ, Kurhanewicz J, Vigneron DB. First hyperpolarized [2-13C]pyruvate MR studies of human brain metabolism. J Magn Reson. 2019; 309:106617. PMCID: PMC6880930 |
| 151 | Barskiy DA, Tayler MCD, Marco-Rius I, Kurhanewicz J, Vigneron DB, Cikrikci S, Aydogdu A, Reh M, Pravdivtsev AN, Hovener JB, Blanchard JW, Wu T, Budker D, Pines A. Zero-field nuclear magnetic resonance of chemically exchanging systems. Nat Commun. 2019; 10(1): 3002. PMCID: PMC6611813 |
| 150 | Behr SC, Aggarwal R, VanBrocklin HF, Flavell RR, Gao K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y. Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrance Antigen in Prostate Cancer. J Nucl Med. 2019; 60(7): 910-916. PMCID: PMC6604687 |
| 149 | Korenchan DE, Gordon JW, Sukumar S, Sriram R, Baligand C, Van Criekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR. Using bidirectional chemical exchange for improved hyperpolarized [13C]bicarbonate pH imaging. Magn Reson Med. 2019; 82(3): 959-972. PMCID: PMC6559833 |
| 148 | Autry AW, Gordon JW, Carvajal L, Mareyam A, Chen HY, Park I, Mammoli D, Vareth M, Chang SM, Wald LL, Xu D, Vigneron DB, Nelson SJ, Li Y. Comparison between 8- and 32-channel phased array receive coils for in vivo hyperpolarized 13C imaging of the human brain. Magn Reson Med. 2019; 82(2): 833-841. PMCID: PMC6612511 |
| 147 | Radoul M, Najac C, Viswanath P, Mukherjee J, Kelly M, Gillespie AM, Chaumeil MM, Eriksson P, Delos Santos R, Pieper RO, Ronen SM. HDAC inhibition in glioblastoma monitored by hyperpolarized 13C MRSI. NMR Biomed. 2019; 32(2): e4044. PMCID: PMC6545173 |
| 146 | Najac C, Radoul M, Le Page LM, Batsios G, Subramani E, Viswanath P, Gillespie AM, Ronen SM. In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma. Sci Rep. 2019; 9(1): 3402. PMCID: PMC6399277 |
| 145 | Zhu X, Gordon JW, Bok RA, Kurhanewicz J, Larson PEZ. Dynamic diffusion-weighted hyperpolarized 13C imaging based on a slice-selective double spin echo sequence for measurements of cellular transport. Magn Reson Med. 2019; 81(3): 2001-2010. PMCID: PMC6347546 |
| 144 | Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW. Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies. J Magn Rson. 2019; 301: 73-79. PMCID: PMC7170546 |
| 143 | Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB. Hyperpolarized 13C MRI: State of the Art and Future Directions. Radiology. 2019; 291(2): 273-284. PMCID: PMC6490043 |
| 142 | Bok R, Lee J, Sriram R, Keshari K, Sukumar S, Daneshmandi S, Korenchan DE, Flavell RR, Vigneron DB, Kurhanewicz J, Seth P. The Role of Lactate Metabolism in Prostate Cancer Progression and Metastases Revealed by Dual-Agent Hyperpolarized 13C MRSI. Cancers (Basel). 2019; 11(2). PMCID: PMC6406929 |
| 141 | Walker CM, Fuentes D, Larson PEZ, Kundra V, Vigneron DB, Bankson JA. Effects of excitation angle strategy on quantitative analysis of hyperpolarized pyruvate. Magn Reson Med. 2019; 81(6): 3754-3762. PMCID: PMC6435389 |
| 140 | Chen HY, Gordon JW, Bok RA, Cao P, von Morze C, van Criekinge M, Milshteyn E, Carvajal L, Hurd RE, Kurhanewicz J, Vigneron DB, Larson PEZ. Pulse sequence considerations for quantification of pyruvate-to-lactate conversion kPL in hyperpolarized 13C imaging. NMR Biomed. 2019; 32(3): e4052. PMCID: PMC6380928 |
| 139 | Tang SJ, Milshteyn E, Reed G, Gordon J, Bok R, Zhu X, Zhu Z, Vigneron DB, Larson PEZ. A regional bolus tracking and real-time B1 calibration method for hyperpolarized 13C MRI. Magn Reson Med. 2019; 81(2): 839-851. PMCID: PMC6289616 |
| 138 | Gordon JW, Chen HY, Autry A, Park I, Van Criekinge M, Mammoli D, Milshteyn E, Bok R, Xu D, Li Y, Aggarwal R, Chang S, Slater JB, Ferrone M, Nelson S, Kurhanewicz J, Larson PEZ, Vigneron DB. Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients. Magn Reson Med. 2019; 81(4): 2702-2709. PMCID: PMC6372313 |
| 137 | Kurhanewicz J, Vigneron DB, Ardenkjaer-Larsen JH, Bankson JA, Brindle K, Cunningham CH, Gallagher FA, Keshari KR, Kjaer A, Laustsen C, Mankoff DA, Merritt ME, Nelson SJ, Pauly JM, Lee P, Ronen S, Tyler DJ, Rajan SS, Spielman DM, Wald L, Zhang X, Malloy CR, Rizi R. Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology. Neoplasia. 2019; 21(1): 1-16. PMCID: PMC6260457 |
| 136 | Lee JE, Diederich CJ, Bok R, Sriram R, Santos RD, Noworolski SM, Salgaonkar VA, Adams MS, Vigneron DB, Kurhanewicz J. Assessing high-intensity focused ultrasound treatment of prostate cancer with hyperpolarized 13C dual-agent imaging of metabolism and perfusion. NMR Biomed. 2019; 32(10): e3962. PMCID: PMC6338537 |
| 135 | 2019 Publications (135 and above) Korenchan DE, Flavell RR. Spatiotemporal pH Heterogeneity as a Promoter of Cancer Progression and Therapeutic Resistance. Cancers (Basel). 2019;11(7):1026. PMCID: PMC6678451. |
| 134 | Sriram R, Sun J, Villanueva-Meyer J, Mutch C, Delos Santos J, Peters J, Korenchan DE, Neumann K, Van Criekinge M, Kurhanewicz J, Rosenberg O, Wilson D, Ohliger MA. Detection of Bacteria-Specific Metabolism Using Hyperpolarized [2-13C]Pyruvate. ACS Infect Dis. 2018; 4(5): 797-805. PMCID: PMC6008482 |
| 133 | Sriram R, Nguyen J, Santos JD, Nguyen L, Sun J, Vigneron S, Van Criekinge M, Kurhanewicz J, MacKenzie JD. Molecular detection of inflammation in cell models using hyperpolarized 13C pyruvate. Theranostics. 2018; 8(12): 3400-3407. PMCID: PMC6010986 |
| 132 | Qin H, Carroll VN, Sriram R, Villanueva-Meyer JE, von Morze C, Wang ZJ, Mutch CA, Keshari KR, Flavell RR, Kurhanewicz J, Wilson DM. Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes. Sci Rep. 2018; 8(1): 7928. PMCID: PMC5962598 |
| 131 | Truillet C, Parker MFL, Huynh LT, Wei J, Jami KM, Wang YH, Shen YS, Sriram R, Wilson DM, Kurhanewicz J, Evans MJ. Measuring glucocorticoid receptor expression in vivo with PET. Oncotarget. 2018; 9(29): 20399-20408. PMCID: PMC5945515 |
| 130 | Larson PEZ, Chen HY, Gordon JW, Korn N, Maidens J, Arcak M, Tang S, van Criekinge M, Carvajal L, Mammoli D, Bok R, Aggarwal R, Ferrone M, Slater JB, Nelson SJ, Kurhanewicz J, Vigneron DB. Investigation of analysis methods for hyperpolarized 13C-pyruvate metabolic MRI in prostate cancer patients. NMR Biomed. 2018; 31(11): e3997. PMCID: PMC6392436 |
| 129 | Sriram R, Gordon J, Baligand C, Ahamed F, Delos Santos J, Qin H, Bok RA, Vigneron DB, Kurhanewicz J, Larson PEZ, Wang ZJ. Non-Invasive Assessment of Lactate Production and Compartmentalization in Renal Cell Carcinomas Using Hyperpolarized 13C Pyruvate MRI. Cancers (Basel). 2018; 10(9). PMCID: PMC6162434 |
| 128 | Autry AW, Hashizume R, James CD, Larson PEZ, Vigneron DB, Park I. Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging. 2018; 2018: 3215658. PMCID: PMC6098895 |
| 127 | Maidens J, Gordon JW, Chen HY, Park I, Van Criekinge M, Milshteyn E, Bok R, Aggarwal R, Ferrone M, Slater JB, Kurhanewicz J, Vigneron DB, Arcak M, Larson PEZ. Spatio-temporally constrained reconstruction for hyperpolarized carbon-13 MRI using kinetic models. IEEE Trans Med Imaging. 2018; 31(12): 2603-2612. PMCID: PMC6279499 |
| 126 | Li N, Liu S, Hu X, Luo C, Zhang X, Li Y. Electromagnetic Field and Radio Frequency Circuit Co-Simulation for Magnetic Resonance Imaging Dual-Tuned Radio Frequency Coils. IEEE Trans Magn. 2018; 54(3). PMCID: PMC5947962 |
| 125 | Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR. Late-Stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI. Chem Commun (Camb). 2018; 54(41): 5233-5236. PMCID: PMC6054790 |
| 124 | Jiang W, Larson PEZ, Lustig M. Simultaneous Auto-calibration and Gradient Delays Estimation (SAGE) in non-Cartesian Parallel MRI using Low-rank Constraints. Magn Reson Med. 2018; 80(5): 2006-2016. PMCID: PMC6107389 |
| 123 | Chen HY, Larson PEZ, Gordon JW, Bok RA, Ferrone M, van Criekinge M, Carvajal L, Cao P, Pauly JM, Kerr AB, Park I, Slater JB, Nelson SJ, Munster PN, Aggarwal R, Kurhanewicz J, Vigneron DB. Technique development of 3D dynamic CS-EPSI for hyperpolarized 13C pyruvate MR molecular imaging of human prostate cancer. Magn Reson Med. 2018; 80(5): 2062-2072. PMCID: PMC6107425 |
| 122 | Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Larson PEZ, Vigneron DB. Using a local low rank plus sparse reconstruction to accelerate dynamic hyperpolarized 13C imaging using the bSSFP sequence. J Magn Reson. 2018; 290: 46-59. PMCID: PMC6054792 |
| 121 | von Morze C, Reed GD, Larson PE, Mammoli D, Chen AP, Tropp J, Van Criekinge M, Ohliger MA, Kurhanewicz J, Vigneron DB, Merritt ME. In vivo hyperpolarization transfer in a clinical MRI scanner. Magn Reson Med. 2018; 80(2): 480-487. PMCID: PMC5910192 |
| 120 | Gordon JW, Hansen RB, Shin PJ, Feng Y, Vigneron DB, Larson PEZ. 3D hyperpolarized C-13 EPI with calibrationless parallel imaging. J Magn Reson. 2018; 289: 92-99. PMCID: PMC5856653 |
| 119 | Milshteyn E, von Morze C, Gordon JW, Zhu Z, Larson PEZ, Vigneron DB. High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-13C]pyruvate and [1-13C]lactate with spectral suppression of alanine and pyruvate-hydrate. Magn Reson Med. 2018; 80(3): 1048-1060. PMCID: PMC5980670 |
| 118 | von Morze C, Allu PKR, Chang GY, Marco-Rius I, Milshteyn E, Wang ZJ, Ohliger MA, Gleason CE, Kurhanewicz J, Vigneron DB, Pearce D. Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance. Sci Rep. 2018; 8(1): 2088. PMCID: PMC5794967 |
| 117 | Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ. Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies. Magn Reson Med. 2018; 80(3): 864-873. PMCID: PMC5980662 |
| 116 | von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ. Direct assessment of renal mitochondrial redox state using hyperpolarized 13C-acetoacetate. Magn Reson Med. 2018; 79(4): 1862-1869. PMCID: PMC5815327 |
| 115 | von Morze C, Tropp J, Chen AP, Marco-Rius I, Van Criekinge M, Skloss TW, Mammoli D, Kurhanewicz J, Vigneron DB, Ohliger MA, Merritt ME. Sensitivity enhancement for detection of hyperpolarized 13C MRI probes with 1H spin coupling introduced by enzymatic transformation in vivo. Magn Reson Med. 2018; 80(1): 36-41. PMCID: PMC5876091 |
| 114 | 2018 Publications (113 and above)
Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. Diffusion-weighted imaging of hyperpolarized [13C]urea in mouse liver. J Magn Reson Imaging. 2018; 47(1): 141-151. PMCID: PMC5645231 |
| 113 | Baligand C, Qin H, True-Yasaki A, Gordon JW, von Morze C, Santos JD, Wilson DM, Raffai R, Cowley PM, Baker AJ, Kurhanewicz J, Lovett DH, Wang ZJ. Hyperpolarized 13C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model. NMR Biomed. 2017; 30(10). PMCID: PMC5618802 |
| 112 | Guglielmetti C, Najac C, Didonna A, Van der Linden A, Ronen SM, Chaumeil MM. Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model. Proc Natl Acad Sci USA. 2017; 114(33): E6982-E6991. PMCID: PMC5565402 |
| 111 | Aggarwal R, Vigneron DB, Kurhanewicz J. Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Androgen Ablation Therapy in Prostate Cancer. Eur Urol. 2017; 72(6): 1028-1029. PMCID: PMC5723206 |
| 110 | Shin PJ, Zhu Z, Camarda R, Bok RA, Zhou AY, Kurhanewicz J, Goga A, Vigneron DB. Cancer recurrence monitoring using hyperpolarized [1-13C]pyruvate metabolic imaging in murine breast cancer model. Magn Reson Imaging. 2017; 43: 105-109. PMCID: PMC5632580 |
| 109 | Chen HY, Larson PEZ, Bok RA, von Morze C, Sriram R, Delos Santos R, Delos Santos J, Gordon JW, Bahrami N, Ferrone M, Kurhanewicz J, Vigneron DB. Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion. Cancer Res. 2017; 77(12): 3207-3216. PMCID: PMC5484421 |
| 108 | Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR. Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging. Analyst. 2017; 142(9): 1429-1433. PMCID: PMC5462110 |
| 107 | Milshteyn E, von Morze C, Reed GD, Shang H, Shin PJ, Zhu Z, Chen HY, Bok R, Goga A, Kurhanewicz J, Larson PE, Vigneron DB. Development of high resolution 3D hyperpolarized carbon-13 MR molecular imaging techniques. Magn Reson Imaging. 2017; 38: 152-162. PMCID: PMC5360530 |
| 106 | Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M. Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13C]dihydroxyacetone. Magn Reson Med. 2017; 77(1): 65-73. PMCID: PMC5191913 |
| 105 | Shang H, Sukumar S, von Morze C, Bok RA, Marco-Rius I, Kerr A, Reed GD, Milshteyn E, Ohliger MA, Kurhanewicz J, Larson PE, Pauly JM, Vigneron DB. Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses. Magn Reson Med. 2017; 78(3): 963-975. PMCID: PMC5400740 |
| 104 | Gordon JW, Milshteyn E, Marco-Rius I, Ohliger M, Vigneron DB, Larson PE. Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects. Magn Reson Med. 2017; 78(3): 1087-1092. PMCID: PMC5391314 |
| 103 | Ohliger MA, von Morze C, Marco-Rius I, Gordon J, Larson PE, Bok R, Chen HY, Kurhanewicz J, Vigneron D. Combining hyperpolarized 13C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism. Magn Reson Med. 2017; 77(6): 2356-2363. PMCID: PMC5156580 |
| 102 | von Morze C, Chang GY, Larson PE, Shang H, Allu PK, Bok RA, Crane JC, Olson MP, Tan CT, Marco-Rius I, Nelson SJ, Kurhanewicz J, Pearce D, Vigneron DB. Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13C-lactate and 13C-pyruvate in kidney and liver. Magn Reson Med. 2017; 77(4): 1429-1437. PMCID: PMC5074920 |
| 101 | Marco-Rius I, Cao P, von Morze C, Merritt M, Moreno KX, Chang GY, Ohliger MA, Pearce D, Kurhanewicz J, Larson PEZ, Vigneron DB. Multiband Spectral-Spatial RF Excitation for Hyperpolarized [2-13C]Dihydroxyacetone 13C-MR Metabolism Studies. Magn Reson Med. 2017; 77(4): 1419-1428. PMCID: PMC5040611 |
| 100 | Gordon JW, Vigneron DB, Larson PE. Development of a symmetric echo planar imaging framework for clinical translation of rapid dynamic hyperpolarized 13C imaging. Magn Reson Med. 2017; 77(2): 826-832. PMCID: PMC4992668 |
| 99 | 2017 Publications (98 and above)
Park I, von Morze C, Lupo JM, Ardenkjaer-Larsen JH, Kadambi A, Vigneron DB, Nelson SJ. Investigating Tumor Perfusion by Hyperpolarized 13C MRI with Comparison to Conventional Gadolinium Contrast-Enhanced MRI and Pathology in Orthotopic Human GBM Xenografts. Magn Reson Med. 2017; 77(2): 841-847. PMCID: PMC4991955 |
| 98 | Cao P, Shin PJ, Park I, Najac C, Marco-Rius I, Vigneron DB, Nelson SJ, Ronen SM, Larson PE. Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing. Magn Reson Med. 2016; 76(2): 369-79. PMCID: PMC4945498 |
| 97 | Reed GD, von Morze C, Verkman AS, Koelsch BL, Chaumeil MM, Lustig M, Ronen SM, Bok RA, Sands JM, Larson PE, Wang ZJ, Larsen JH, Kurhanewicz J, Vigneron DB. Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry. Tomography. 2016; 2(2): 125-135. PMCID: PMC4996281 |
| 96 | Koelsch BL, Sriram R, Keshari KR, Leon Swisher C, Van Criekinge M, Sukumar S, Vigneron DB, Wang ZJ, Larson PE, Kurhanewicz J. Separation of extra- and intracellular metabolites using hyperpolarized 13C diffusion weighted MR. J Magn Reson. 2016; 270: 115-123. PMCID: PMC5448422 |
| 95 | Cao P, Zhang X, Park I, Najac C, Nelson SJ, Ronen S, Larson PE. (1) H-(13) C independently tuned radiofrequency surface coil applied for in vivo hyperpolarized MRI. Magn Reson Med. 2016; 76(5): 1612-1620. PMCID: PMC4879596 |
| 94 | Maidens J, Gordon JW, Arcak M, Larson PEZ. Optimizing flip angles for metabolic rate estimation in hyperpolarized carbon-13 MRI. IEEE Transactions on Medical Imaging. 2016; 35(11): 2403-2412. PMCID: PMC5134417 |
| 93 | Sriram R, Van Criekinge M, DeLos Santos J, Keshari KR, Wilson DM, Peehl D, Kurhanewicz J, Wang ZJ. Non-invasive differentiation of benign renal tumors from clear cell renal cell carcinomas using clinically translatable hyperpolarized 13C pyruvate magnetic resonance. Tomography. 2016; 2(1): 35-42. PMCID: PMC4876723 |
| 92 | Radoul M, Chaumeil MM, Eriksson P, Wang AS, Phillips JJ, Ronen SM. MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. Mol Cancer Ther. 2016; 15(5): 1113-22. PMCID: PMC4873419 |
| 91 | Viswanath P, Najac C, Izquierdo-Garcia JL, Pankov A, Hong C, Eriksson P, Costello JF, Pieper RO, Ronen SM. Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters. Oncotarget. 2016; 7(73): 34942-55. PMCID: PMC5085201 |
| 90 | Chaumeil MM, Radoul M, Najac C, Eriksson P, Viswanath P, Blough MD, Chesnelong C, Luchman HA, Cairncross JG, Ronen SM. Hyperpolarized 13C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring. Neuroimage Clin. 2016; 12: 180-9. PMCID: PMC4939422 |
| 89 | Najac C, Chaumeil MM, Kohanbash G, Guglielmetti C, Gordon JW, Okada H, Ronen SM. Detection of inflammatory cell function using 13C magnetic resonance spectroscopy of hyperpolarized [6-(13)C]-arginine. Sci Rep. 2016; 6: 3197. PMCID: PMC4979036 |
| 88 | Gordon JW, Larson PEZ. Pulse Sequences for Hyperpolarized MRS. eMagRes. 2016, Vol 5: 1229-1246. doi:10.1002/97804700349590.emrstm1451. |
| 87 | Kurhanewicz J, Vigneron DB. Magnetic Resonance Spectroscopy of Prostate Cancer. John Wiley & Sons, Ltd. eMagRes. 2016, Vol 5: 1–22. DOI 10.1002/9780470034590.emrstm1433. |
| 86 | Korenchan DE, Flavell RR, Baligand C, Sriram R, Neumann K, Sukumar S, VanBrocklin H, Vigneron DB, Wilson DM, Kurhanewicz J. Dynamic nuclear polarization of biocompatible 13C-enriched carbonates for in vivo pH imaging. Chem Commun (Camb). 2016; 52(14): 3030-3. PMCID: PMC4864526 |
| 85 | Shang H, Larson P, Kerr A, Reed G, Sukumar S, Elkhaled A, Gordon JW, Ohliger MA, Pauly JM, Lustig M, Vigneron DB. Multiband RF Pulses with Improved Performance via Convex Optimization. J Magn Reson. 2016; 262: 81-90. PMCID: PMC4716678 |
| 84 | Feng Y, Gordon JW, Shin PJ, von Morze C, Lustig M, Larson PEZ, Ohliger MA, Carvajal L, Tropp J, Pauly JM, Vigneron DB. Development and testing of hyperpolarized 13C MR calibrationless parallel imaging. J Magn Reson. 2016; 262: 1-7. PMCID: PMC4864033 |
| 83 | Chen Y, Kim H, Bok R, Sukumar S, Mu X, Sheldon RA, Barkovich AJ, Ferrierro DM, Xu D. Pyruvate to Lactate Metabolic Changes during Neurodevelopment Measured Dynamically Using Hyperpolarized 13C Imaging in Juvenile Murine Brain. Dev Neurosci. 2016; 38(1): 34-40. PMCID: PMC4732911 |
| 82 | von Morze C, Bok RA, Ohliger MA, Zhu Z, Vigneron DB, Kurhanewicz J. Hyperpolarized [13C]ketobutyrate, a molecular analog of pyruvate with modified specificity for LDH Isoforms. Magn Reson Med. 2016; 75(5): 1894-900. PMCID: PMC4868134 |
| 81 | Shang H, Skloss T, von Morze C, Carvajal L, Van Criekinge M, Milshteyn E, Larson PE, Hurd RE, Vigneron DB. Handheld electromagnet carrier for transfer of hyperpolarized carbon-13 samples. Magn Reson Med. 2016; 75(2): 917-22. PMCID: PMC4567531 |
| 80 | 2016 Publications (79 and above)
Jiang W, Lustig M, Larson PE. Concentric rings K-space trajectory for hyperpolarized 13C MR spectroscopic imaging. Magn Reson Med. 2016; 75(1): 19-31. PMCID: PMC4476971 |
| 79 | Carroll VN, Truillet C, Shen B, Flavell RR, Shao X, Evans MJ, VanBrocklin HF, Scott PJ, Chin FT, Wilson DM. [(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography. Chem Commun (Camb). 2016; 52(27):4888-90.PMCID: PMC4854297 |
| 78 | Keshari KR, Wilson DM, Van Criekinge M, Sriram R, Koelsch BL, Wang ZJ, VanBrocklin HF, Peehl DM, O’Brien T, Sampath D, Carano RA, Kurhanewicz J. Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor. Prostate. 2015; 75(14): 1601-9. PMCID: PMC4537380 |
| 77 | Flavell RR, von Morze C, Blecha JE, Korenchan D, van Criekinge M, Sriram R, Gordon J, Chen HY, Sukumar S, Bok R, Wang ZJ, Vigneron D, Larson P, Kurhanewicz J, Wilson DM. Application of Good’s buffers to pH imaging using hyperpolarized 13C MRI. Chem Comm (Camb). 2015; 51(74): 14119-22. PMCID: PMC4854286 |
| 76 | Sriram R, van Criekinge M, Hansen AF, Wang Z, Vigneron D, Wilson DM, Keshari K, Kurhanewicz J. Real-time Measurement of Hyperpolarized Lactate Production and Efflux as a Biomarker of Tumor Aggressiveness in an MR compatible 3D Cell Culture Bioreactor. NMR Biomed. 2015; 28(9): 1141-9. PMCID: PMC4537810 |
| 75 | Leon Swisher C, Koelsch B, Sukumar S, Sriram R, Delos Santos R, Wang ZJ, Kurhanewicz J, Vigneron D, Larson PE. Dynamic UltraFast 2D Exchange Spectroscopy (UF-EXSY) of Hyperpolarized Substrates. JMR. 2015; 257: 102-109. PMCID: PMC4515769 |
| 74 | Li Y, Park I, Nelson SJ. Imaging Tumor Metabolism using in vivo MR Spectroscopy. Cancer J. 2015; 21(2): 123-8. PMCID: PMC4429803 |
| 73 | Shin P, Larson P, Uecker M, Reed G, Kerr A, Tropp J, Ohliger M, Nelson S, Pauly J, Lustig M, Vigneron D. Chemical Shift Separation with Controlled Aliasing for Hyperpolarized 13C Metabolic Imaging. Magn Reson Med. 2015; 74(4): 978-89. PMCID: PMC4390401 |
| 72 | Koelsch BL, Reed GD, Keshari KR, Chaumeil MM, Bok R, Ronen SM, Vigneron DB, Kurhanewicz J, Larson PE. Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized 13C metabolites. Magn Reson Med. 2015; 74(3): 622-33. PMCID: PMC4362805 |
| 71 | Tang S, Jiang W, Chen HY, Bok R, Vigneron DB, Larson PE. A 2DRF pulse sequence for bolus tracking in hyperpolarized 13C imaging. Magn Reson Med. 2015; 74(2): 506-12. PMCID: PMC4336852 |
| 70 | 2015 Publications (70 and above)
Keshari K, Wilson D, Sai Victor, Bok R; Jen KY, Larson P, Van Criekinge M, Kurhanewicz J, Wang ZJ. Non-invasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance. Diabetes. 2015; 64(2): 344-52. PMCID: PMC4303960 |
| 69 | Pang Y, Wu B, Jiang X, Vigneron DB, Zhang X. Tilted microstrip phased arrays with improved electromagnetic decoupling for ultrahigh-field magnetic resonance imaging. Medicine (Baltimore). 2014; 93(28): e311. PMCID: PMC4603100 |
| 68 | Sriram R, Kurhanewicz J, Vigneron D. Hyperpolarized Carbon-13 MRI and MRS Studies. in Encyclopedia of Magnetic Resonance, eds J. Griffiths and P. Bottomley, John Wiley: Chichester. eMagRes. 3: 1-14, 2014. DOI: 10.1002/9780470034590.emrstm1253 |
| 67 | Wilson DM, Kurhanewicz J. Hyperpolarized 13C MR for Molecular Imaging of Prostate Cancer. J Nucl Med. 2014; 55(10): 1567-72. PMCID: PMC4349324 |
| 66 | Chen L, Shu Y, Liang X, Chen EC, Yee SW, Zur AA, Li S, Xu L, Keshari KR, Lin MJ, Chien HC, Zhang Y, Morrissey KM, Liu J, Ostrem J, Younger NS, Kurhanewicz J, Shokat KM, Ashrafi K, Giacomini KM. OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad Sci USA. 2014; 111(27): 9983-8. PMCID: PMC4103324 |
| 65 | Park I, Mukherjee J, Ito M, Chaumeil MM, Jalbert LE, Gaensler K, Ronen SM, Nelson SJ, Pieper RO. Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells. Cancer Res. 2014; 74(23): 7115-24. PMCID: PMC4253720 |
| 64 | Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M, Lane AN, Higashi RM, Fan TW, Pandolfi PP, Sukhatme VP, Seth P. Targeting lactate dehydrogenase-A (LDH-A) inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor initiating cells. Cell Metabolism. 2014; 19(5): 795-809. PMCID: PMC4096909 |
| 63 | von Morze C, Carvajal L, Reed GD, Swisher CL, Tropp J, Vigneron DB. Directly detected 55Mn MRI: Application to phantoms for human hyperpolarized 13C MRI development. Magn Reson Imaging. 2014; 32(10): 1165-70. PMCID: PMC4254142 |
| 62 | Shin PJ, Larson PE, Ohliger MA, Elad M, Pauly JM, Vigneron DB, Lustig M. Calibrationless parallel imaging reconstruction based on structured low-rank matrix completion. Magn Reson Med. 2014; 72(4): 959-70. PMCID: PMC4025999 |
| 61 | Keshari KR, Wilson DM. Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization. Chem Soc Rev. 2014; 43(5): 1627-59. PMCID: PMC4086923 |
| 60 | Bahrami N, Swisher CL, von Morze C, Vigneron DB, Larson PE. Kinetic and perfustion modeling of hyperpolarized 13C pyruvate and urea in cancer with arbitrary RF flip angles. Quant Imaging Med Surg. 2014; 4(1): 24-32. PMCID: PMC3947982 |
| 59 | Chaumeil MM, Larson PE, Woods SM, Cai L, Eriksson P, Robinson AE, Lupo JM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma. Cancer Res. 2014; 74(16): 4247-57. PMCID: PMC4134724 |
| 58 | Pang Y, Jiang X, Zhang X. Sparse Parallel Transmission on Randomly Perturbed Spiral K-space Trajectory. Quant Imaging Med Surg. 2014; 4(2): 106-111. PMCID: PMC4014875 |
| 57 | Pang Y, Yu B, Zhang X. Enhancement of the Low Resolution Imaging Quality using Randomly Sampled Data for Multi-Slice MR Imaging. Quant Imaging Med Surg. 2014; 4(2): 136-144. PMCID: PMC4014877 |
| 56 | Aggarwal R, Kurhanewicz J. Prostate cancer in 2013: The changing role of imaging in clinical care. Nature Reviews Urology. 2014; 11: 75-77. PMCID: PMC4057014 |
| 55 | Pang Y, Wong E, Yu B, Zhang X. Design and Numerical Evaluation of A Volume Coil Array for Parallel MR Imaging at Ultrahigh Fields. Quant Imaging Med Surg. 2014; 4(1): 50-56. PMICD: PMC3947986 |
| 54 | Pang Y, Yu B, Vigneron D, Zhang X. Quadrature Transmit Array Design Using Single-Feed Circularly Polarized Patch Antenna for Parallel Transmission in MR Imaging. Quant Imaging Med Surg. 2014; 4(1): 11-18. PMCID: PMC3947984 |
| 53 | Reed G, von Morze C, Bok R, Koelsch B, Van Criekinge M, Smith K, Shang H, Larson P, Kurhanewicz J, Vigneron D. High Resolution C-13 MRI With Hyperpolarized Urea: in vivo T(2) Mapping and N-15 Labeling Effects. IEEE Trans Med Imaging. 2014; 33(2): 362-71. PMCID: PMC4011557 |
| 52 | Park I, Larson PEZ, Tropp JL, Carvajal L, Reed G, Bok R, Robb F, Bringas J, Kells A, Pivirotto P, Bankiewicz K, Vigneron DB, Nelson SJ. Dynamic Hyperpolarized Carbon-13 Metabolic MR Imaging of Non-Human Primate Brain. Magn Reson Med. 2014; 71(1): 19-25. PMCID: PMC4041734 |
| 51 | Swisher CL, Larson PE, Kruttwig K, Kerr AB, Hu S, Bok RA, Goga A, Pauly JM, Nelson SJ, Kurhanewicz J, Vigneron DB. Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS. Magn Reson Med. 2014; 71(1): 1-11. PMCID: PMC3659200 |
| 50 | 2014 Publications (50 and above)
von Morze C, Bok RA, Reed GD, Ardenkjaer-Larsen JH, Kurhanewicz J, Vigneron DB. Simultaneous multiagent hyperpolarized 13C perfusion imaging. Magn Reson Med. 2014; 72(6): 1599-609. PMCID: PMC4077988 |
| 49 | Nelson SJ, Kurhanewicz J, Vigneron DB, Larson PE, Harzstark AL, Ferrone M, van Criekinge M, Chang JW, Bok R, Park I, Reed G, Carvajal L, Small EJ, Munster P, Weinberg VK, Ardenkjaer-Larsen JH, Chen AP, Hurd RE, Odegardstuen LI, Robb FJ, Tropp J, Murray JA. Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate. Sci Transl Med. 2013; 5(198): 198ra108. PMCID: PMC4201045. Note: This clinical trial research was not funded by the center, but benefitted from its equipment and infrastructure. |
| 48 | Finsterbusch J, Busch MG, Larson PE. Signal scaling improves the signal-to-noise ratio of measurements with segmented 2D-selective radiofrequency excitations. Magn Reson Med. 2013; 70(6): 1491-9. PMCID: PMC4987130 |
| 47 | Chaumeil MM, Larson PE, Yoshihara HA, Danforth OM, Vigneron DB, Nelson SJ, Pieper RO, Phillips JJ, Ronen SM. Non-invasive in vivo assessment of IDH1 mutational status in glioma. Nat Commun. 2013; 4: 2429. PMCID: PMC3908661 |
| 46 | Li Y, Yu B, Pang Y, Vigneron D, Zhang X. Planar quadrature RF transceiver design using common-mode differential-mode (CMDM) transmission line method for 7T MR Imaging. PLoS One. 2013; 8(11): e80428. PMCID: PMC3827179 |
| 45 | Xing Y, Reed GD, Pauly JM, Kerr AB, Larson PE. Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates. J Magn Reson. 2013; 234: 75-81. PMCID: PMC3765634 |
| 44 | Li Y, Wang C, Yu B, Vigneron D, Chen W, Zhang X. Image homogenization using pre-emphasis method for high field MRI. Quant Imaging Med Surg. 2013; 3(4): 217-223. PMCID: PMC3759133 |
| 43 | Crane JC, Olson MP, Nelson SJ. SIVIC: Open-Source, Standards-Based Software for DICOM MR Spectroscopy Workflows. International Journal of Biomedical Imaging. 2013; 2013:169526. PMCID: PMC3732592 |
| 42 | Keshari KR, Sriram R, Van Criekinge M, Wilson DM, Wang ZJ, Vigneron DB, Peehl DM, Kurhanewicz J. Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor. Prostate. 2013; 73(11): 1171-81. PMCID: PMC3976546 |
| 41 | Keshari KR, Sai V, Wang ZJ, Vanbrocklin HF, Kurhanewicz J, Wilson DM. Hyperpolarized [1-13C]dehydroascorbate MR spectroscopy in a murine model of prostate cancer: comparison with 18F-FDG PET. J Nucl Med. 2013; 54(6): 922-8. PMCID: PMC3682497 |
| 40 | Nelson SJ, Ozhinsky E, Li Y, Park I, Crane J. Strategies for Rapid in vivo 1H and hyperpolarized 13C MR Spectroscopic Imaging. Journal of Magnetic Resonance. 2013; 229: 187-97. PMCID: PMC3808990 |
| 39 | Koelsch BL, Keshari KR, Peeters TH, Larson PE, Wilson DM, Kurhanewicz J. Diffusion MR of hyperpolarized 13C molecules in solution. Analyst. 2013; 138(4): 1011-4. PMCID: PMC3568999 |
| 38 | Keshari KR, Sriram R, Koelsch BL, Van Criekinge M, Wilson DM, Kurhanewicz J, Wang ZJ. Hyperpolarized 13C-Pyruvate Magnetic Resonance Reveals Rapid Lactate Export in Metastatic Renal Cell Carcinomas. Cancer Res. 2013; 73(2): 529-38. PMCID: PMC3548990 |
| 37 | Ohliger MA, Larson PE, Bok RA, Shin P, Hu S, Tropp J, Robb F, Carvajal L, Nelson SJ, Kurhanewicz J, Vigneron DB. Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance spectroscopic imaging (MRSI). J Magn Reson Imaging. 2013; 38(3): 701-13. PMCID: PMC3759833 |
| 36 | Lodi A, Woods SM, Ronen SM. Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells. NMR Biomed. 2013; 26(3): 299-306. PMCID: PMC3529990 |
| 35 | Larson PEZ, Hurd RE, Kerr AB, Pauly JM, Bok RA, Kurhanewicz J, Vigneron DB. Perfusion and diffusion sensitive 13C stimulated-echo MRSI for metabolic imaging of cancer. Magn Reson Imaging. 2013; 31(5): 635-42. PMCID: PMC3626756 |
| 34 | Hu S, Larson PE, Van Criekinge M, Leach AM, Park I, Leon C, Zhou J, Shin PJ, Reed G, Keselman P, von Morze C, Yoshihara H, Bok RA, Nelson SJ, Kurhanewicz J, Vigneron DB. Rapid sequential injections of hyperpolarized [1-(13)C]pyruvate in vivo using a sub-kelvin, multi-sample DNP polarizer. Magn Reson Imaging. 2013; 31(4): 490-6. PMCID: PMC3625683 |
| 33 | Pang Y, Zhang X. Interpolated compressed sensing for 2D multiple slice fast MR imaging. PLoS One. 2013; 8(2): e56098. PMCID: PMC3568040 |
| 32 | 2013 Publications (32 and above)
Park I, Hu S, Ozawa T, Ito M, Mukherjee J, Phillips JJ, James CD, Pieper RO, Ronen SM, Vigneron DB, Nelson SJ. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging. Magn Reson Med. 2013; 70(1):33-9. PMCID: PMC3630274 |
| 31 | Pang Y, Yu B, Zhang X. Hepatic fat assessment using advanced Magnetic Resonance Imaging. Quant Imaging Med Surg. 2012; 2(3): 213-8. PMCID: PMC3496514 |
| 30 | Keshari KR, Kurhanewicz J, Macdonald JM, Wilson DM. Generating contrast in hyperpolarized 13C MRI using ligand-receptor interactions. Analyst. 2012; 137(15): 3427-9. PMCID: PMC3600417 |
| 29 | Larson PE, Kerr AB, Leon Swisher C, Pauly JM, Vigneron DB. A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates. J Magn Reson. 2012; 225: 71-80. PMCID: PMC3531583 |
| 28 | von Morze C, Sukumar S, Reed GD, Larson PE, Bok RA, Kurhanewicz J, Vigneron DB. Frequency-specific SSFP for hyperpolarized 13C metabolic imaging at 14.1 T. Magn Reson Imaging. 2012; 31(2): 163-70. PMCID: PMC3651030 |
| 27 | Wu B, Li Y, Wang C, Vigneron DB, Zhang X. Multi-reception strategy with improved SNR for multichannel MR imaging. PLoS One. 2012; 7(8):e42237. PMCID: PMC3411773 |
| 26 | Venkatesh HS, Chaumeil MM, Ward CS, Haas-Kogan DA, James CD, Ronen SM. Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma. Neuro Oncol. 2012; 14(3): 315-25. PMCID: PMC3280799 |
| 25 | Chaumeil MM, Ozawa T, Park I, Scott K, James CD, Nelson SJ, Ronen SM. Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma. Neuroimage. 2012; 59(1): 193-201. PMCID: PMC3196046 |
| 24 | Hu S, Yoshihara HA, Bok R, Zhou J, Zhu M, Kurhanewicz J, Vigneron DB. Use of hyperpolarized [1-(13)C] pyruvate and [2-(13)C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat. Magn Reson Imaging. 2012; 30(10): 1367-72. PMCID: PMC3480972 |
| 23 | von Morze C, Bok RA, Sands JM, Kurhanewicz J, Vigneron DB. Monitoring urea transport in rat kidney in vivo using hyperpolarized 13C magnetic resonance imaging. Am J Physiol Renal Physiol. 2012; 302(12): F1658-62. PMCID: PMC3378100 |
| 22 | Reed GD, Larson PE, von Morze C, Bok R, Lustig M, Kerr AB, Pauly JM, Kurhanewicz J, Vigneron DB. A Method for Simultaneous Echo Planar Imaging of Hyperpolarized 13C Pyruvate and 13C Lactate. J Magn Reson. 2012; 217: 41-7. PMCID: PMC3326401 |
| 21 | Wu B, Zhang X, Wang C, Li Y, Pang Y, Lu J, Xu D, Majumdar S, Nelson SJ, Vigneron DB. Flexible transceiver array for ultrahigh field human MR imaging. Magn Reson Med. 2012; 68(4): 1332-8. PMCID: PMC3350759 |
| 20 | von Morze C, Larson PEZ, Hu S, Yoshihara HAI, Bok RA, Goga A, Ardenkjaer-Larsen JH, Vigneron DB. Investigating tumor perfusion and metabolism using multiple hyperpolarized 13C compounds: HP001, pyruvate and urea. Magnetic Resonance Imaging. 2012; 30(3): 305-11. PMCID: PMC3393100 |
| 19 | Wang C, Li Y, Wu B, Xu D, Nelson SJ, Vigneron DB, Zhang X. A practical multinuclear transceiver volume coil for in vivo MRI/MRS at 7T. Magn Reson Imaging. 2012; 30(1): 78-84. PMCID: PMC3277811 |
| 18 | Wu B, Wang C, Lu J, Pang Y, Nelson SJ, Vigneron DB, Zhang X. Multi-channel microstrip transceiver arrays using harmonics for high field MR imaging in humans. IEEE Trans Med Imaging. 2012; 31(2): 183-91. PMCID: PMC3277810 |
| 17 | Pang Y, Xie Z, Xu D, Kelley DA, Nelson SJ, Vigneron DB, Zhang X. A dual-tuned quadrature volume coil with mixed λ/2 and λ/4 microstrip resonators for multinuclear MRSI at 7T. Magn Reson Imaging. 2012; 30(2): 290-8. PMCID: PMC3254778 |
| 16 | 2012 Publications (16 and above)
Larson PE, Kerr AB, Reed GD, Hurd RE, Kurhanewicz J, Pauly JM, Vigneron DB. Generating Super Stimulated-Echoes in MRI and Their Application to Hyperpolarized C-13 Diffusion Metabolic Imaging. IEEE Trans Med Imaging. 2012; 31(2): 265-75. PMCID: PMC3274664 |
| 15 | Larson PEZ, Gold GE. Science to practice: Can inflammatory arthritis be monitored by using MR imaging with injected hyperpolarized 13C-pyruvate? Radiology. 2011; 259(2): 309-10. PMCID: PMC6939944 |
| 14 | Chen AP, Hurd RE, Gu YP, Wilson DM, Cunningham CH. 13C MR reporter probe system using dynamic nuclear polarization. NMR Biomed. 2011; 24(5): 514-20. PMID: 21674653 |
| 13 | Pang Y, Zhang X, Xie Z, Wang C, Vigneron DB. Common-mode differential-mode (CMDM) method for double-nuclear MR signal excitation and reception at ultrahigh fields. IEEE Trans Med Imaging. 2011; 30(11): 1965-73. PMCID: PMC3277813 |
| 12 | von Morze C, Reed G, Shin P, Larson PE, Hu S, Bok R, Vigneron DB. Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate. J Magn Reson. 2011; 211(2): 109-13. PMCID: PMC3143308 |
| 11 | Park I, Bok R, Ozawa T, Phillips JJ, James CD, Vigneron DB, Ronen SM, Nelson SJ. Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging. J Magn Reson Imaging. 2011; 33(6): 1284-90. PMCID: PMC4983457 |
| 10 | Lippert AR, Keshari KR, Kurhanewicz J, Chang CJ. A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent. J Am Chem Soc. 2011; 133(11): 3776-9. PMCID: PMC3060273 |
| 9 | Larson PE, Hu S, Lustig M, Kerr AB, Nelson SJ, Kurhanewicz J, Pauly JM, Vigneron DB. Fast dynamic 3D MR spectroscopic imaging with compressed sensing and multiband excitation pulses for hyperpolarized 13C studies. Magn Reson Med. 2011; 65(3): 610-619. PMCID: PMC3021589 |
| 8 | Pang Y, Zhang X. Precompensation for mutual coupling between array elements in parallel excitation. Quant Imaging Med Surg. 2011; 1(1): 4-10. PMCID: PMC3496487 |
| 7 | Tropp J, Lupo JM, Chen AP, Calderon P, McCune D, Grafendorfer T, Ozturk-Isik E, Larson PE, Hu S, Yen YF, Robb F, Bok R, Schulte R, Xu D, Hurd R, Vigneron D, Nelson S. Multi-Channel Metabolic Imaging, with SENSE reconstruction, of Hyperpolarized [1-13C] Pyruvate in a Live Rat at 3.0 tesla on a Clinical MR Scanner. Journal of Magnetic Resonance. 2011; 208(1): 171-7. PMCID: PMC3387549 |
| 6 | Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev EY, Comment A, Cunningham CH, Deberardinis RJ, Green GG, Leach MO, Rajan SS, Rizi RR, Ross BD, Warren WS, & Malloy CR. Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia. 2011; 13(2) 81-97. PMCID: PMC3033588 |
| 5 | von Morze C, Larson PE, Hu S, Keshari K, Wilson DM, Ardenkjaer-Larsen JH, Goga A, Bok R, Kurhanewicz J, Vigneron DB. Imaging of blood flow using hyperpolarized [13C]urea in preclinical cancer models. J Magn Reson Imaging. 2011; 33(3): 692-7. PMCID: PMC3566235 |
| 4 | Pang Y, Wu B, Wang C, Vigneron DB, Zhang X. Numerical Analysis of Human Sample Effect on RF Penetration and Liver MR Imaging at Ultrahigh Field. Concepts Magn Reson Part B Magn Reson Eng. 2011; 39B(4): 206-216. PMCID: PMC3277816 |
| 3 | Keshari KR, Kurhanewicz J, Bok R, Larson PE, Vigneron DB, Wilson DM. Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging. Proc Natl Acad Sci USA. 2011; 108(46): 18606-11. PMCID: PMC3219134 |
| 2 | Hu S, Zhu M, Yoshihara HAI, Wilson DM, Keshari KR, Shin P, Reed G, von Morze C, Bok R, Larson PEZ, Kurhanewicz J, Vigneron DB. In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-13C]alanine. Magnetic Resonance Imaging. 2011; 29(8): 1035-1040. PMCID: PMC3172390 |
| 1 | 2011 Publications (1 and above)
Hu S, Balakrishnan A, Bok RA, Anderton B, Larson PE, Nelson SJ, Kurhanewicz J, Vigneron DB, Goga A. 13C-Pyruvate Imaging Reveals Alterations in Glycolysis that Precede c-Myc-Induced Tumor Formation and Regression. Cell Metabolism. 2011; 14(1): 131-42. PMCID: PMC3858338 |
