2023 HMTRC Workshop
Photo credits 2023 HMTRC Workshop: UCSF Campus Life Services/Marco Sanchez
The April 2023 Hyperpolarized Carbon-13 MRI Technology Development Workshop includes academic & vendor lectures, hands-on training and discussions on dissolution DNP methodology, polarizer instrumentation, MR Sequence and Acquisitions, Pre-clinical HP Chemistry Preps, Human HP Investigational Dose Formulation & Production, Clinical Translation Methods, Clinical Trial Support, and Analysis & Display Software.
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2023 Workshop Video Presentations
Day 1:
Center TR&D Presentations
8:00 AM - 9:00 AM
• Introductions: HMTRC Director, Dr. Dan Vigneron PhD & Chair of Radiology & Biomedical Imaging, Dr. Christopher Hess MD, PhD
• Center Updates on Hyperpolarized C-13 MRI Technology Development: HMTRC Director, Dr. Dan Vigneron PhD
• Hyperpolarized C-13 MRI Clinical Translation Update: Dr. Jane Wang MD, HP Medical Director
• Technology Development for Polarizer and Detector Instrumentation: Dr. Jeremy Gordon PhD & Duy Dang PharmD
• Development of Novel Hyperpolarized (HP) MR Molecular Imaging Probes Tested in Realistic Preclinical Models and Correlative Science Studies: Drs. John Kurhanewicz PhD & Renuka Sriram PhD
• Acquisition and Analysis Methods for Hyperpolarized MR Data: Drs. Duan Xu PhD & Peder Larson PhD
Day 1:
Plenary Presentations
9:30 AM - 11:30 AM
- Dr. Jae Mo Park PhD, University of Texas Southwestern: Imaging Mitochondrial Metabolism using Hyperpolarized C-13 Pyruvate
- Dr. Kayvan Keshari PhD, Memorial Sloan Kettering Cancer Center, NY: Can we make metabolism great again?
- Dr. Chris Laustsen PhD, Aarhus University: Is there a place for cardiac hyperpolarized [1-13C]pyruvate in the clinical toolbox?
- Dr. Chuck Cunningham PhD, University of Toronto: Hyperpolarized C-13 MRI of the Human Brain
- Dr. Gigin Lin MD PhD, Chang Gung Memorial Hospital, Taiwan: Hyperpolarized C-13 MRI Evaluate Immune Metabolism
- Dr. Jan Ardenkjaer-Larsen PhD, Technical University of Denmark: Hyperpolarized MR
- Dr. Robert Bok MD PhD, UCSF: Update of Hyperpolarized C-13 MRI for Active Surveillance in Prostate Cancer Subjects
Day 1:
Plenary Presentations
3:45 PM - 4:45 PM
- Dr. James Kempf PhD, Bruker Scientist: Versatile, High-throughput d-DNP with Bruker
- Dr. Titus Lanz PhD, RAPID Biomedical GmbH: A Dual Tuned C-13/H-1 Array for Torso Application
- Dr. Sella Brosh MD, NVision Imaging Technologies: NVISION Hyperpolarized MRI made simple
Day 1:
Keynote Presentations
5:00 PM - 6:00 PM
• Keynote Lecture by Dr. Donna Peehl PhD, UC San Francisco: Preclinical HP C-13 MRI: Looking Back and Looking Forward
• Keynote Lecture by Dr. Ferdia Gallagher MD PhD, University of Cambridge: The Potential for Metabolic Imaging
Day 2: Plenary Presentations
9:30 AM - 10:30 AM
- Dr. Stephen Lai MD PhD, UT MD Anderson Cancer Center: Developing a Quantifiable Imaging-Based Biomarker
- Dr. Ivan De Kouchkovsky MD – Rahul Aggarwal MD, UCSF: Emerging Clinical Applications of Hyperpolarized C-13 MRI in Prostate Cancer
Day 2:
Plenary Presentations
1:30 PM - 3:30 PM
- Dr. Myriam Chaumeil PhD, UCSF: Recent advances in preclinical HP C-13 metabolic neuroimaging
- Dr. Vlad Zaha MD PhD, University of Texas Southwestern: Lessons from Using Hyperpolarized C-13 labeled Substrates in Cardio-Oncology
- Dr. Yaewon Kim PhD, UCSF: Clinical HP C-13 MR Molecular Imaging: Probes beyond [1-13C]Pyruvate
- Dr. Adam Retter MD PhD Candidate, University College London: C-13 Pyruvate Hyperpolarised MR in patients with prostate cancer on active surveillance
- Dr. Yan Li MD PhD, UCSF: Imaging Tumor Metabolism for Improved Management of Patients with Glioma
- Dr. Dan Crooks MS PhD, NIH/NCI: Metabolic and Mitochondrial Heterogeneity in Fumarate Hydratase-Deficient Renal Tumors
Day 2:
Plenary Presentations
3:45 PM - 6:00 PM
- Dr. Matthew Merritt PhD, University of Florida: Investigating Pancreas Metabolism with Hyperpolarized [1-13C]Pyruvate
- Dr. Pavithra Viswanath PhD, UCSF: Probing the pentose phosphate pathway in brain tumors using hyperpolarized C-13 imaging
- Alba Herrero Gomez, Institute for BioEngineering Catalonia, Barcelona: Hyperpolarization-enhanced NMR and MRI methods for tissue engineering applications
- Dr. Xiaoxi Liu PhD, UCSF: Metabolite-Specific 3D bSSFP Sequences for Hyperpolarized C-13 MRI
- Dr. Jan-Bernd Höevener PhD, University of Kiel: SpinAlinger dDNP 2.5 years and 370 dissolutions in
- Dr. Hsin-Yu Chen PhD, UCSF: Hyperpolarized 13C Pyruvate MR-Assisted Longitudinal Risk Stratification in Prostate Cancer Patient – From Surveillance to Surgery