2023 HMTRC Workshop

Photo credits 2023 HMTRC Workshop: UCSF Campus Life Services/Marco Sanchez

The April 2023 Hyperpolarized Carbon-13 MRI Technology Development Workshop includes academic & vendor lectures, hands-on training and discussions on dissolution DNP methodology, polarizer instrumentation, MR Sequence and Acquisitions, Pre-clinical HP Chemistry Preps, Human HP Investigational Dose Formulation & Production, Clinical Translation Methods, Clinical Trial Support, and Analysis & Display Software.
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2023 Workshop Video Presentations



Day 1:
Center TR&D Presentations

8:00 AM - 9:00 AM

Introductions: HMTRC Director, Dr. Dan Vigneron PhD & Chair of Radiology & Biomedical Imaging, Dr. Christopher Hess MD, PhD

Center Updates on Hyperpolarized C-13 MRI Technology Development: HMTRC Director, Dr. Dan Vigneron PhD

• Hyperpolarized C-13 MRI Clinical Translation Update: Dr. Jane Wang MD, HP Medical Director

• Technology Development for Polarizer and Detector Instrumentation: Dr. Jeremy Gordon PhD & Duy Dang PharmD

Development of Novel Hyperpolarized (HP) MR Molecular Imaging Probes Tested in Realistic Preclinical Models and Correlative Science Studies: Drs. John Kurhanewicz PhD & Renuka Sriram PhD

Acquisition and Analysis Methods for Hyperpolarized MR Data: Drs. Duan Xu PhD & Peder Larson PhD 


Day 1: 
Plenary Presentations

9:30 AM - 11:30 AM


Day 1: 
Plenary Presentations

3:45 PM - 4:45 PM

Day 1:
Keynote Presentations

5:00 PM - 6:00 PM

Keynote Lecture by Dr. Donna Peehl PhD, UC San Francisco: Preclinical HP C-13 MRI: Looking Back and Looking Forward

Keynote Lecture by Dr. Ferdia Gallagher MD PhD, University of Cambridge: The Potential for Metabolic Imaging


Day 2: Plenary Presentations
9:30 AM - 10:30 AM

Day 2: 
Plenary Presentations

1:30 PM - 3:30 PM

  • Dr. Myriam Chaumeil PhD, UCSF: Recent advances in preclinical HP C-13 metabolic neuroimaging
  • Dr. Vlad Zaha MD PhD, University of Texas Southwestern: Lessons from Using Hyperpolarized C-13 labeled Substrates in Cardio-Oncology
  • Dr. Yaewon Kim PhD, UCSF: Clinical HP C-13 MR Molecular Imaging: Probes beyond [1-13C]Pyruvate
  • Dr. Adam Retter MD PhD Candidate, University College London: C-13 Pyruvate Hyperpolarised MR in patients with prostate cancer on active surveillance
  • Dr. Yan Li MD PhD, UCSF: Imaging Tumor Metabolism for Improved Management of Patients with Glioma
  • Dr. Dan Crooks MS PhD, NIH/NCI: Metabolic and Mitochondrial Heterogeneity in Fumarate Hydratase-Deficient Renal Tumors

Day 2: 
Plenary Presentations

3:45 PM - 6:00 PM

  • Dr. Matthew Merritt PhD, University of Florida: Investigating Pancreas Metabolism with Hyperpolarized [1-13C]Pyruvate
  • Dr. Pavithra Viswanath PhD, UCSF: Probing the pentose phosphate pathway in brain tumors using hyperpolarized C-13 imaging
  • Alba Herrero Gomez, Institute for BioEngineering Catalonia, Barcelona: Hyperpolarization-enhanced NMR and MRI methods for tissue engineering applications
  • Dr. Xiaoxi Liu PhD, UCSF: Metabolite-Specific 3D bSSFP Sequences for Hyperpolarized C-13 MRI
  • Dr. Jan-Bernd Höevener PhD, University of Kiel: SpinAlinger dDNP 2.5 years and 370 dissolutions in 
  • Dr. Hsin-Yu Chen PhD, UCSF: Hyperpolarized 13C Pyruvate MR-Assisted Longitudinal Risk Stratification in Prostate Cancer Patient – From Surveillance to Surgery