2024 HMTRC Workshop
Photo credits 2024 HMTRC Workshop: fallfoto, Elisabeth Fall 2024
The April 2024 Hyperpolarized Carbon-13 MRI Technology Development Workshop includes lectures, hands-on training and discussions on dissolution DNP methodology, polarizer instrumentation, MR Sequence and Acquisitions, Pre-clinical HP Chemistry Preps, Human HP Investigational Dose Formulation & Production, Clinical Translation Methods, Clinical Trial Research, and Analysis & Display Software.
View Agenda
2024 Workshop Video Presentations
Click the links below to view released presentations from the 2024 Workshop:
Day 1:
Center TR&D Presentations
8:00 AM - 9:00 AM
- Welcome & Introductions: Dr. Dan Vigneron, HMTRC Director PhD & Dr. Christopher Hess MD, PhD, Chair of Radiology & Biomedical Imaging
- Hyperpolarized C-13 MRI Clinical Translation Update: Dr. Zhen Jane Wang MD, HP Medical Director
- TR&D1: Technology Development for Polarizer and Detector Instrumentation: HMTRC Director, Dr. Dan Vigneron PhD & Duy Dang PharmD
- TR&D2: Development of Novel Hyperpolarized (HP) MR Molecular Imaging Probes Tested in Realistic Preclinical Models and Correlative Science Studies: Drs. Renuka Sriram PhD & John Kurhanewicz PhD
- TR&D3: Acquisition and Analysis Methods for Hyperpolarized MR Data: Drs. Peder Larson PhD & Duan Xu PhD
Day 1:
Plenary Presentations
9:30 AM - 11:30 AM
- Dr. Chris Laustsen PhD, Aarhus University: Aarhus Neuro Imaging – Fast and Small - Large and Slow
- Dr. Jae Mo Park PhD, University of Texas Southwestern: Imaging PDH and PC Flux Using Dissolution DNP: Developments & Applications
- Dr. Shun Kishimoto PhD, NIH/NCI: Summary of Preclinical Metabolic MRI Studies at NIH
- Dr. Jan Ardenkjaer-Larsen PhD, Technical University of Denmark: Hyperpolarized MR: The Clinical Translation of Dissolution-DNP
- Dr. James Bankson PhD, UT MD Anderson Cancer Center: A Collection of Short Stories About Area-Under-the-Curve Ratios in HP MRI
- Dr. Ferdia Gallagher MD PhD, University of Cambridge: Biological Validation of Hyperpolarised C-13 MRI
- Dr. Robert Bok MD PhD, UCSF: Neuroendocrine Tumors (NET): A Novel Application for HP C-13 MRI
Day 1:
Plenary Presentations
3:45 PM - 4:45 PM
- Dr. Kayvan Keshari PhD, Memorial Sloan Kettering Cancer Center, NY: Can We Learn More About Brain Metabolism?
- Dr. Damian Tyler PhD, University of Oxford, UK: Overcoming the Challenges of Hyperpolarized MR
Day 1:
Keynote Presentations
5:00 PM - 6:00 PM
- Keynote Lecture by Dr. Mary McLean, University of Cambridge, UK: Traces
- Keynote Lecture by Dr. Michael Ohliger MD PhD, UCSF: Clinical Translation of HP C-13 MRI: View From a Radiologist
Day 2: Plenary Presentations
9:30 AM - 10:30 AM
- Dr. James Kempf PhD, Bruker Scientist: Versatile, High-throughput d-DNP
- Dr. Andreas Korzowski PhD, German Cancer Research Center: HYPERBOLIC – Alternative Data Sampling Strategies & Open-Source Sequence Design for HP C-13 MRI
- Dr. Ivan De Kouchkovsky MD, UCSF: Emerging Clinical Applications of Hyperpolarized C-13 MRI in Prostate Cancer
Day 2:
Plenary Presentations
1:00 PM - 3:00 PM
- Dr. Charlie Khemtong PhD, University of Florida: In Vivo Evaluations of Esterase-Sensitive Hyperpolarized C-13 Ethyl Acetyl Carbonate
- Dr. Mathilde Hauge Lerche PhD, Technical University of Denmark: On the Path to Translation: Mouse Alzheimer´s Study in a 3T Clinical Scanner
- Dr. Dirk Mayer PhD, University of Maryland: Preclinical and Clinical Brain Imaging Applications of Hyperpolarized C-13 Pyruvate
- Dr. Jan-Bernd Höevener PhD, University of Kiel: From Mushrooms to Microbes to Men: An Update from Kiel
- Dr. Andreas Schmidt PhD, University of Freiburg: Rapid Parahydrogen-Based Carbon-13 Hyperpolarization and Fast MRI for Tumor Investigations
- Dr. Ching-Yi Hsieh PhD, Chang Gung Memorial Hospital, Taiwan: The Progress Report on HP Carbon-13 Clinical Trials
Day 2:
Plenary Presentations
3:15 PM - 4:30 PM
- Dr. Irene Marco-Rius PhD, IBEC/Vitala, Barcelona Spain: Hyperpolarization-enhanced NMR and MRI methods for tissue engineering applications
- Dr. Myriam Chaumeil PhD, UCSF: Hyperpolarized C-13 MR Imaging of Alzheimer’s Disease
- Dr. Elton Montrazi PhD, Weizmann Institute of Science: Glucose or Pyruvate as Optimal Metabolic Cancer Reporter? The Deuterium MR Spectroscopic Imaging Evidence
